67130-96-5

Upstream product

• 3506-68-1 4-(2-bromophenyl)-2-butanone 
• 64-17-5 ethanol 
• 2039-88-5 2-bromostyrene 
• 66192-11-8 diethyl 2-(2-bromobenzyl)propan-1,3-dioate 
• 15115-58-9 3-(2-bromophenyl)propionic acid 
• 52221-92-8 3-(2-bromo-phenyl)-propan-1-ol 
• 58380-12-4 <(2-bromophenyl)methyl>propanedicarboxylic acid 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 72454-54-7 4-(2-bromophenyl)but-3-en-2-one 
• 6630-33-7 ortho-bromobenzaldehyde 
• 468082-55-5 trans-4-(2-bromophenyl)-3-buten-2-one 
• 1378939-10-6 (E)-4-(2-bromophenyl)but-3-en-2-ol 
• 917-54-4 methyllithium 
• 107408-16-2 3-(o-bromophenyl)propanal 

Downstream Products

• 79044-18-1 4-(o-Bromophenyl)-2-bromobutane 
• 2344-70-9 1-phenyl-3-butanol 
• 107408-53-7 5-Methylene-3-oxo-7-phenyl-2-(triphenyl-λ⁵-phosphanylidene)-heptanoic acid ethyl ester 
• 107408-52-6 4-(1-Methyl-indan-1-yl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-butyric acid ethyl ester 
• 107408-15-1 (Z)-7-(2-Bromo-phenyl)-5-methyl-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-hept-4-enoic acid ethyl ester 
• 107408-18-4 ethyl 7-(2-bromophenyl)-5-methyl-3-oxo-2-(triphenylphosphoranylidene)-4-heptenoate 
• 767-58-8 1-methylindane 

Relevant academic research and scientific papers

Switchable asymmetric bio-epoxidation of α,β-unsaturated ketones

Efficient asymmetric bio-epoxidation of electron-deficient α,β-unsaturated ketones was realized via a tandem reduction-epoxidation-dehydrogenation cascade, which proceeds in a switchable manner to afford either chiral epoxy ketones or allylic epoxy alcoho

Synthesis of 2-aryl-substituted chromans by intramolecular C-O bond formation

A synthetic route for the preparation of 2-aryl-substituted chromans from commercially available starting materials and utilizing either a palladium- or copper-catalyzed intramolecular cyclization of aryl bromides is described. Chromans with stereocontrol at C-2 can thus be obtained via a palladium-catalyzed asymmetric allylic etherification procedure utilizing a chiral indole-phosphine oxazoline (IndPHOX) ligand. Georg Thieme Verlag Stuttgart · New York.

A reaction for sp3-sp3 C-C bond formation via cooperation of Lewis acid-promoted/Rh-catalyzed C-H bond activation

A new method for intermolecular sp3-sp3 C-C bond formation between primary aliphatic alcohol and olefin by use of a RhCl(PPh3)3 (cat.)/BF3·OEt2 (2.5 equiv)/BuBr (0.5 equiv)/toluene system was first disclosed, which possessed quite significant utilities for organic synthesis, especially for that of secondary alcohols. The most significant aspect is the discovery that rhodium-catalyzed C-H bond activation of alcohols is feasible under Lewis acid-promoted conditions. Copyright

Catalyst for aromatic C—O, C—N, and C—C bond formation

The present invention is directed to a transition metal catalyst, comprising a Group 8 metal and a ligand having the structure wherein R, R′ and R″ are organic groups having 1-15 carbon atoms, n=1-5, and m=0-4. The present invention is also directed to a method of forming a compound having an aromatic or vinylic carbon-oxygen, carbon-nitrogen, or carbon-carbon bond using the above catalyst. The catalyst and the method of using the catalyst are advantageous in preparation of compounds under mild conditions of approximately room temperature and pressure.

Lithium-Halogen Exchange-Initiated Cyclization Reactions. 3. Intramolecular Conjugate Addition Reactions of Unsaturated Acylphosphoranes

The lithium-halogen exchange-initiated intramolecular conjugate addition reactions of some model unsaturated acylphosphoranes have been examined.The effects of halide type, chain length, and acceptor substitution pattern on the feasibility of ring construction were studied.The lithium-bromine exchange reactions in two 2-bromooaryl acceptors were found to be too slow, relative to competing side reactions, to allow practical carbocycle syntheses while 3-,4-,5-, and 6-membered carbocycles are formed in good to excellent yields from precursors that are vinyl and saturated primary iodides.Highly efficient intramolecular conjugate addition reactions to β,β-disubstituted acceptor units are possible, and intermediate anions from intramolecular conjugate addition reactions are readily captured with electrophiles.