671771-00-9

Upstream product

• 141-97-9 ethyl acetoacetate 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 109-77-3 malononitrile 
• 108-26-9 3-methyl-2-pyrazoline-5-one 
• 3206-39-1 3-methyl-2-pyrazoline-5-one 
• 7803-57-8 hydrazine hydrate 
• 2972-76-1 2-(2,4-dichlorobenzylidene)malononitrile 
• 132712-71-1 5-hydroxy-3-methylpyrazole 

Relevant academic research and scientific papers

Mild, four-component synthesis of 6-amino-4-aryl-3-methyl-1,4- dihydropyrano[2,3-c]pyrazole-5-carbonitriles catalyzed by titanium dioxide nano-sized particles

A convenient and efficient solvent-free procedure is described for preparation of 6-amino-4-aryl-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5- carbonitriles by four-component reaction of hydrazine hydrate, ethyl acetoacetate, aryl aldehyde, and malononitri

Magnetized melamine-modified polyacrylonitrile (PAN@melamine/Fe3O4) organometallic nanomaterial: Preparation, characterization, and application as a multifunctional catalyst in the synthesis of bioactive dihydropyrano [2,3-c]pyrazole

An efficient magnetic polymer-based nanomaterial was prepared in three main steps including synthesis of polyacrylonitrile (PAN), modification of PAN with melamine, and magnetization of the PAN@melamine compound by in situ construction of Fe3O

Nano cobalt ferrite encapsulated-silica particles bearing melamine as an easily recyclable catalyst for the synthesis of dihydropyrano[2,3-c]pyrazoles under green conditions

In this research, it was displayed an efficient method for synthesis of 6-amino-2,4-dihydropyrano[2,3-c] pyrazol-5-carbonitrile derivatives by using CoFe2O4 silica supported bearing melamine as a magnetic nanocatalyst. This nanocompo

Preparation and characterization of a novel organic–inorganic hybrid nanostructure: application in synthesis of spirocompounds

Abstract: Immobilization and heterogenization of acidic/basic groups or organic tags on inorganic supports have found many important applications in recent years. In this investigation, a new hybrid organic–inorganic nanostructure was prepared. The struct

DABA MNPs: A new and efficient magnetic bifunctional nanocatalyst for the green synthesis of biologically active pyrano[2,3-: C] pyrazole and benzylpyrazolyl coumarin derivatives

In this work, a new core-shell magnetic silica nanocatalyst functionalized with 3,4-diaminobenzoic acid (Fe3O4@SiO2@PTS-DABA) was successfully prepared and characterized using different spectroscopic methods or techniques including FT-IR, FE-SEM, VSM, XRD

Copper-immobilized ionic liquid as an alternative to organic solvents in the one-pot synthesis of bioactive dihydropyrano[2,3-c]pyrazole derivatives

In this study, a novel Cu-immobilized ionic liquid (IL)was designed, characterized, and employed as both promoter and solvent in the synthesis of some dihydropyrano[2,3-c]pyrazoles. The synthesized ionic liquid was characterized by 1H NMR, sup

Catalyst-free green synthesis of dihydropyrano[2,3-c]pyrazole scaffolds assisted by ethylene glycol (E-G) as a reusable and biodegradable solvent medium

Abstract: We revealed a catalyst-free, green and rapid one-pot four-component tandem strategy for the preparation of dihydropyrano[2,3-c]pyrazoles – a biologically significant scaffold – via Knoevenagel-Michael cyclocondensation based on green chemistry p

An expedient and eco-friendly approach for multicomponent synthesis of dihydropyrano[2,3-c]pyrazoles using nano-Al2O3/BF3/Fe3O4 as reusable catalyst

The pyranopyrazole derivatives have many biological activities. They were synthesized via a four-component coupling of aromatic aldehyde, malononitrile, ethyl acetoacetate and hydrazine hydrate. In this study, dihydropyrano[2,3-c]pyrazoles have been synth

Synthesis and antimicrobial study of 1,4-dihydropyrano[2,3-c]pyrazole derivatives in the presence of amino-functionalized silica-coated cobalt oxide nanostructures as catalyst

In this research a series of pyranopyrazoles were efficiently synthesized via the one-pot four-component reactions of ethyl acetoacetate, hydrazinehydrate, aldehydes and malononitrile in the presence of Co3O4@SiO2-tNH