671809-76-0

Upstream product

• 671809-80-6 p-tolyl 2-azido-3,4,6-tri-O-benzyl-2-deoxy-D-thioglucopyranoside 
• 671809-74-8 4',5-O-dibenzyl-perazidonebramine 
• 468065-22-7 O-3-azido-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diazido-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-1,3-diazido-1,2,3-trideoxy-D-myo-inositol 
• 468065-27-2 perbenzyl-perazidotobramyicn 
• 100-39-0 benzyl bromide 

Downstream Products

• 671809-82-8 4-(2,6-diamino-2,3,6-dideoxy-α-D-glucopyranosyl)-6-(2-amino-2-deoxy-1-α-D-glucopyranosyl)-2-deoxystreptamine 

Relevant academic research and scientific papers

Targeting RNAs with tobramycin analogues

(Chemical equation presented). A library of 4,6-linked analogues of the drug tobramycin with various mono- or diaminosugars attached to the 6-position of the two-ring core has been prepared (see scheme; Bn = benzyl, Tol = p-tolyl). The compounds were scre

Glyco-optimization of aminoglycosides: New aminoglycosides as novel anti-infective agents

Glyco-optimization (OPopSTM) of aminoglycosides has been performed by replacing the existing sugar moiety with a variety of sugar derivatives. Glycosylation of the 6-position of nebramine provided a library of novel 4,6-linked aminoglycosides (

Aminoglycoside antibiotics as novel anti-infective agents

This invention relates to novel aminoglycoside compounds having antibacterial and anti-infective activity and to pharmaceutical compositions, methods of making and methods of treatment employing the same.