67193-51-5Relevant academic research and scientific papers
A Mild and General One-Pot Synthesis of Densely Functionalized Diaryliodonium Salts
Qin, Linlin,Hu, Bao,Neumann, Kiel D.,Linstad, Ethan J.,McCauley, Katelyenn,Veness, Jordan,Kempinger, Jayson J.,DiMagno, Stephen G.
supporting information, p. 5919 - 5924 (2015/09/22)
Diaryliodonium salts are powerful and widely used arylating agents in organic chemistry. Here we report a scalable synthesis of densely functionalized diaryliodonium salts from aryl iodides under mild conditions. This two-step, one-pot process has remarkable functional group tolerance, is compatible with commonly employed acid-labile protective group strategies, avoids heavy metal and transition metal reagents, and provides a direct route to stable precursors to PET imaging agents.
Bisisobenzofurandionylantracene compound, preparation method thereof and organic insulationg layer using the same
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Paragraph 0100; 0101; 0105; 0106, (2016/10/10)
The present invention relates to a bis-isobenzofuran-dionyl antracene compound, a manufacturing method thereof and an organic insulation film using the same wherein the bis-isobenzofuran-dionyl antracene compound can be used for manufacturing an organic insulator with high heat resistance. According to the present invention, a manufacturing method of the bis-isobenzofuran-dionyl antracene compound uses suzuki-coupling, which has few limitations for functional groups and high selectivity for reaction and accordingly has few side reactions, dehydration cyclization reaction and hydrolysis under base or acid conditions, thereby manufacturing bis-isobenzofuran-dionyl antracene with improved purity and yield.COPYRIGHT KIPO 2015
Aerobic oxidation of cyclohexane using N-hydroxyphthalimide bearing fluoroalkyl chains
Guha, Samar Kumar,Obora, Yasushi,Ishihara, Daisuke,Matsubara, Hiroshi,Ryu, Ilhyong,Ishii, Yasutaka
experimental part, p. 1323 - 1330 (2009/05/30)
The N-hydroxyphthalimide derivatives, F15-and F 17-NHPI, bearing a long fluorinated alkyl chain, were prepared and their catalytic performances were compared with that of the parent compound, N-hydroxyphthalimide (NHPI). The oxidation of cyclohexane under 10 atm of air in the presence of fluorinated F15-or F17-NHPI, cobalt diacetate [Co(OAc)2], and manganese diacetate [Mn(OAc)2] without any solvent at 100°C afforded a mixture of cyclohexanol and cyclohexanone (K/A oil) as major products along with a small amount of adipic acid. It was found that F15-and F17-NHPI exhibit higher catalytic activity than NHPI for the oxidation of cyclohexane without a solvent. However, for the oxidation in acetic acid all of these catalysts afforded adipic acid as a major product in good yield and the catalytic activity of NHPI in acetic acid was almost the same as those of F15-and F 17-NHPI. The oxidation by F15-and F17-NHPI catalysts in trifluorotoluene afforded K/A oil in high selectivity with little formation of adipic acid, while NHPI was a poor catalyst under these conditions, forming K/A oil as well as adipic acid in very low yields. The oxidation in trifluorotoluene by F15-and F17-NHPI catalysts was considerably accelerated by the addition of a small amount of zirconium(IV) acetylacetonate [Zr(acac)4] to the present catalytic system to afford selectively K/A oil, but no such effect was observed in the NHPI-catalyzed oxidation in trifluorotoluene.
Design, Synthesis and Cytotoxicity of 2-Hydroxy-1(H)-isoindole-1,3-dione (HISD) Derivatives Against CEM/O Human Leukemia Cells in vitro
Nandy, Partha,Avramis, Vassilios I.,Lien, Eric J.
, p. 664 - 679 (2007/10/03)
2-Hydroxy-1(H)-isoindole-1,3-dione derivatives (HISDs) possess a hydroxamic acid moiety which is built into an isoindoledione ring. Seven new compounds have been synthesized and tested for cytotoxicity against CEM human leukemia cell lines. Three active c
