672294-77-8Relevant academic research and scientific papers
Desymmetrization of Metalated Cyclohexadienes and Application to the Synthesis of Nephrosteranic Acid
Schleth, Florian,Studer, Armido
, p. 313 - 315 (2004)
Chiral cyclohexadienyl Ti-TADDOLate reacts with aldehydes to provide the corresponding homoallyl alcohols in high yields with excellent diastereo- and high enantioselectivities (see scheme). The new method has been used as the key step in an efficient syn
