67249-05-2Relevant articles and documents
Alkoxy/halostyryl benzoic acids: Synthesis, crystal structure, and study of mesomorphic and photophysical properties
Muhammad, Khushi,Rauf, M. Khawar,Tahir, M. Nawaz,Hameed, Shahid
, p. 32 - 45 (2017/09/07)
Alkoxy/halostyrylbenzoic acids were synthesized and evaluated for their mesomorphic and photophysical properties. The trans geometry of the molecules was established by the presence of large coupling constants in 1H-NMR spectra and confirmed fu
Discovery of highly selective and potent monoamine oxidase B inhibitors: Contribution of additional phenyl rings introduced into?2-aryl-1,3,4-oxadiazin-5(6H)-one
Lee, Jungeun,Lee, Yeongcheol,Park, So Jung,Lee, Joohee,Kim, Yeong Shik,Suh, Young-Ger,Lee, Jeeyeon
, p. 365 - 378 (2017/03/10)
Monoamine oxidase B (MAO-B) is a flavin adenine dinucleotide (FAD)-containing enzyme that plays a major role in the oxidative deamination of biogenic amines and neurotransmitters. Inhibiting MAO-B activity is a promising approach in the treatment of neuro
Preparation of Vinyl Arenes by Nickel-Catalyzed Reductive Coupling of Aryl Halides with Vinyl Bromides
Liu, Jiandong,Ren, Qinghua,Zhang, Xinghua,Gong, Hegui
supporting information, p. 15544 - 15548 (2016/12/09)
This work emphasizes the synthesis of substituted vinyl arenes by reductive coupling of aryl halides with vinyl bromides under mild and easy-to-operate nickel-catalyzed reaction conditions. A broad range of aryl halides, including heteroaromatics, and vinyl bromides were employed to yielding products in moderate to excellent yields with high functional-group tolerance. The nickel-catalytic system displays good chemoselectivity between the two C(sp2)-halide coupling partners, thus demonstrating a mechanistic pathway distinct from other stepwise protocols.
Chemoselective and Sequential Palladium-Catalyzed Couplings for the Generation of Stilbene Libraries via Immobilized Substrates
Traficante, Carla I.,Fagundez, Catherine,Serra, Gloria L.,Mata, Ernesto G.,Delpiccolo, Carina M. L.
supporting information, p. 225 - 229 (2016/06/01)
A versatile palladium-catalyzed tandem synthetic sequence to afford E-stilbenes libraries has been developed. Excellent regio- and stereocontrol have been achieved by means of the sequence of Hiyama and Heck cross-couplings. Undesirable homocoupling bypro
Catalytic Semireduction of Internal Alkynes with All-Metal Aromatic Complexes
Deyris, Pierre-Alexandre,Ca?eque, Tatiana,Wang, Yanlan,Retailleau, Pascal,Bigi, Franca,Maggi, Raimondo,Maestri, Giovanni,Malacria, Max
, p. 3266 - 3269 (2015/10/28)
A simple catalytic method involving all-metal aromatic frameworks as precatalysts ensures an efficient route to (Z)-alkenes. Aromatic triangular palladium clusters were used to reduce internal alkynes without any trace of the formation of alkane side products. These trinuclear complexes provide a catalytic system that parallels the activity and selectivity of their best mononuclear peers, and the catalyst likely operates through complementary mechanisms.
Rhodium-catalyzed oxidative decarbonylative Heck-type coupling of aromatic aldehydes with terminal alkenes
Kang, Lei,Zhang, Feng,Ding, Lin-Ting,Yang, Luo
, p. 100452 - 100456 (2015/12/09)
A rhodium-catalyzed oxidative decarbonylative Heck-type coupling of aromatic aldehydes with terminal alkenes to afford 1,2-disubstituted alkenes with good regio- and E-selectivity is developed. This reaction employs readily available aromatic aldehydes as the aryl electrophile counterpart and relies on selected acyl chloride as the crucial additive to activate the rhodium catalyst precursor.
Evidences of release and catch mechanism in the Heck reaction catalyzed by palladium immobilized on highly cross-linked-supported imidazolium salts
Pavia, Cinzia,Giacalone, Francesco,Bivona, Lucia Anna,Salvo, Anna Maria Pia,Petrucci, Chiara,Strappaveccia, Giacomo,Vaccaro, Luigi,Aprile, Carmela,Gruttadauria, Michelangelo
, p. 57 - 62 (2014/04/03)
Palladium (10 wt%) on a highly cross-linked imidazolium-based material was used as catalyst in 0.1 mol% in the Heck reaction between several alkenes and aryl iodides. Products were obtained from good to high yields. Deeper investigations showed a release of Pd species in solution and their capture by the imidazolium-based support. When a sixfold amount of support was employed the re-captured Pd species (0.5-0.6 wt%) were not anymore catalytically active. This result represents a new interesting aspect of this work since the highly cross-linked imidazolium-based material can act also as Pd scavenger avoiding the release of the metal in solution. Important differences between Heck and Suzuki reactions have been evidenced when the reactions were carried out in the presence of the scavenging support.
Controlled photocycloaddition of unsaturated carboxylates intercalated in hydrotalcite clay interlayers
Takagi, Katsuhiko,Shichi, Tetsuya,Usami, Hisanao,Sawaki, Yasuhiko
, p. 4339 - 4344 (2007/10/02)
Photochemical cycloaddition for several unsaturated carboxylates has been studied in the presence of hydrotalcite clays. Syn head-to-head cyclodimers were selectively formed in the irradiation of sodium cinnamates intercalated in the dispersed clays. On the other hand, two isomers of syn head-to-head and syn head-to-tail cyclodimers were formed for the case of (phenylethenyl)benzoates. The degree of intercalation was shown to be dependent on the structures of the carboxylates. X-ray diffraction analyses revealed that the carboxylates are intercalated as a monolayer, which suggests an alternate anti-parallel packing since a clay interlayer possesses two ionic surfaces, top and bottom. The product selectivity was shown to be controlled by the relative distances of double bonds from the ionic surfaces of the clay. The molecular aggregates of intercalated carboxylates were affected by adding photoinactive coadsorbates; the major photochemical processes shifted from photocycloadditions to cis-trans isomerizations and from excimer to monomer fluorescence emissions.
