67253-49-0Relevant academic research and scientific papers
Asymmetric Synthesis of Epoxides using Chiral Sulfimides
Baird, Charlotte P.,Taylor, Paul C.
, p. 893 - 894 (1995)
The sodium salt of (S)-sulfimide 8 reacts with carbonyl compounds to yield (R)-epoxides in 60-64percent yield and 21-70percent e.e.
Asymmetric transfer hydrogenation of prochiral ketones in aqueous media with new water-soluble chiral vicinal diamine as ligand
Ma, Yaping,Liu, Hui,Chen, Li,Cui, Xin,Zhu, Jin,Deng, Jingen
, p. 2103 - 2106 (2007/10/03)
(Matrix presented) An easily accessible water-soluble chiral o-sulfonated 1,2-diphenylethlenediamine 2 and its mono-N-tosylated derivative 3 were synthesized for the first time. The ruthenium-complex-catalyzed reduction of prochiral ketones in aqueous media has been examined by using 3 as ligand and sodium formate as the source of hydrogen. The asymmetric transfer hydrogenation of ω-bromo acetophenones was achieved, in which only formate displacement occurred when formic acid/triethylamine azeotrope was used as the hydrogen donor.
Novel Optical Resolution Methods by Inclusion Crystallisation in Suspension Media and by Fractional Distillation
Toda, Fumio,Tohi, Yasushi
, p. 1238 - 1240 (2007/10/02)
Enantioselective inclusion crystallisation of a hydrophobic oily racemic guest and a crystalline optically active host compound is achieved efficiently by stirring a suspension of both components in hexane or water, allowing enantiomers to be separated by fractional distillation.
Chiral porphyrin imine manganese complex as catalyst for asymmetric epoxidation of styrene derivatives
-
supporting information, (2019/01/25)
New chiral porphyrin imine was synthesized from (S)-3-benzyl-2-methyl-4-phenylbutanal according to dipyrromethane method using trifluoroacetic acid, BF3 etherate, and p-chloranil. Manganese complex of this chiral porphyrin imine ligand was used as catalyst in the asymmetric epoxidation of styrene derivatives possessing different substituents. Styrene derivatives possessing electron withdrawing groups gave the corresponding chiral epoxides in high yield up to 98% and ee up to 99%. The mechanism for the catalytic asymmetric epoxidation was also discussed based on transfer of oxygen.
