67259-63-6

Basic information

• Product Name: Piperidine, 4-[4-(trifluoromethyl)phenyl]-
• Synonyms: Piperidine, 4-[4-(trifluoromethyl)phenyl]-;4-(4-Trifluoromethylphenyl)piperidine
• CAS NO: 67259-63-6
• Molecular Formula: C₁₂H₁₄F₃N
• Molecular Weight: 229.24
• Mol File: 67259-63-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 276 ºC
• Flash Point: 121 ºC
• Appearance: /
• Density: 1.145
• Vapor Pressure: 0.00482mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: Piperidine, 4-[4-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 4-[4-(trifluoromethyl)phenyl]-(67259-63-6)
• EPA Substance Registry System: Piperidine, 4-[4-(trifluoromethyl)phenyl]-(67259-63-6)

Safety Data

• Hazardous Substances Data: 67259-63-6(Hazardous Substances Data)

Usage

Uses

4-(4-Trifluoromethylphenyl)piperidine is used as a reactant in the preparation of N-arylheterocycles as MCH antagonists.

InChI:InChI=1/C12H14F3N/c13-12(14,15)11-3-1-9(2-4-11)10-5-7-16-8-6-10/h1-4,10,16H,5-8H2

Upstream product

• 67259-64-7 1,2,3,6-tetrahydro-4-(α,α,α-trifluoro-p-tolyl)pyridine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 437998-30-6 1-t-Butoxycarbonyl-4-(4-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 138647-49-1 4-Trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 220000-88-4 4-(4-trifluoromethyl-phenyl)-pyridine 
• 30459-17-7 1-[4-(trifluoromethyl)phenyl]piperazine 
• 402-43-7 p-trifluoromethylphenyl bromide 

Downstream Products

• 133229-05-7 1-(4-Nitro-phenoxy)-3-[4-(4-trifluoromethyl-phenyl)-piperidin-1-yl]-propan-2-ol 
• 1361316-84-8 1-(3-hydroxypropyl)-4-[4-(trifluoromethyl)phenyl]piperidine 
• 1268862-81-2 3-(4-fluorophenyl)-2-(4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)quinoxaline-6-carboxylic acid 
• 1268865-74-2 methyl 3-(4-fluorophenyl)-2-(4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)quinoxaline-6-carboxylate 
• 1268865-26-4 methyl 2-phenyl-3-(4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)quinoxaline-6-carboxylate 
• 1181965-76-3 ethyl 4-oxo-1-({4-[4-(trifluoroethyl)phenyl]piperidin-1-yl}methyl)-4H-quinolizine-3-carboxylate 
• 180157-76-0 (2S)-(-)-1-(4-indolyloxy)-3-(4-(4-trifluoromethylphenyl)piperidin-1-yl)-2-propanol ethanedioate 
• 721953-51-1 5,5-bis(4-fluorophenyl)-2-methyl-3-(3-oxo-3-{4-[4-(trifluoromethyl)phenyl]-1-piperidinyl}propyl)-3,5-dihydro-4H-imidazol-4-one 

Relevant articles and documents

PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN

Pyrazolo[1,5-a]pyrimidin-7(4H)-ones of formula (I) inhibit intraflagellar transport and are useful as anticancer agents and as probes of the function of dynein-dependent systems.

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