67276-04-4 Usage
Description
SODIUM TRI-SEC-BUTYLBOROHYDRIDE is a chemical compound that serves as a reducing agent in various chemical reactions. It is known for its ability to facilitate conjugate hydride reduction-initiated tandem cyclization reactions and stereoselective nucleophilic addition reactions, making it a valuable tool in organic synthesis.
Uses
Used in Organic Synthesis:
SODIUM TRI-SEC-BUTYLBOROHYDRIDE is used as a reducing agent for conjugate hydride reduction-initiated tandem cyclization reactions. This application is crucial in the synthesis of complex organic molecules, as it allows for the formation of multiple rings in a single reaction step, increasing the efficiency and selectivity of the process.
Additionally, SODIUM TRI-SEC-BUTYLBOROHYDRIDE is used as a reducing agent for stereoselective nucleophilic addition reactions. This application is important in the synthesis of enantiomerically pure compounds, which are essential in various industries, including pharmaceuticals and agrochemicals. The stereoselectivity of these reactions ensures that the desired enantiomer is formed, reducing the need for further separation and purification steps.
Check Digit Verification of cas no
The CAS Registry Mumber 67276-04-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,2,7 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 67276-04:
(7*6)+(6*7)+(5*2)+(4*7)+(3*6)+(2*0)+(1*4)=144
144 % 10 = 4
So 67276-04-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H27B.Na/c1-7-10(4)13(11(5)8-2)12(6)9-3;/h10-12H,7-9H2,1-6H3;/q-1;+1
67276-04-4Relevant articles and documents
Reaction of Trialkylboranes with Sodium Diethylhydroaluminate in the Presence of 1,4-Diazabicylooctane: a Convenient, General Method for Preparation of Sodium Trialkylhydroborates
Hubbard, John L.
, p. 1639 - 1640 (1989)
Trialkylboranes in tetrahydrofuran solution, even those with exceptionally large steric requirements, react readily with toluene solutions of sodium diethyldihydroaluminate in the presence of 1,4-diazabicyclooctane, resulting in a convenient and general preparation of sodium trialkylhydroborates.
Method for producing alkali metal monohydridoborates and monohydridoaluminates
-
, (2008/06/13)
The invention relates to a method for producing compounds of general formula (A) by reacting an alkali metal hydride with a compound (B) during which the reaction is carried out in the presence of a catalyst that contains boron, whereby: M represents Li, Na, K, Rb or Cs; E represents B or Al, and; X1, X2, X3, independent of one another, represent a secondary or tertiary alkyl group, which is comprised of 2 to 10 atoms, or represent a phenyl group which itself can be alkyl-substituted or they represent an alkoxy group, and the catalyst, which contains boron, or the conversion product thereof with MH is capable of acting as a hydride transfer agent.