672912-09-3Relevant academic research and scientific papers
Synthesis and Characterization of Oxorhenium and Oxotechnetium Complexes with a Novel Tetradentate N3O Bifunctional Agent
Papachristou, Maria,Pirmettis, Ioannis,Siatra-Papastaikoudi, Theodora,Pelecanou, Maria,Tsoukalas, Charalambos,Raptopoulou, Catherine P.,Terzis, Aris,Chiotellis, Efstratios,Papadopoulos, Minas
, p. 3826 - 3830 (2007/10/03)
The novel tetradentate N3O bifunctional agent 3-hydroxy-4-[2-(2′-pyridinecarboxamido)acetylamino]benzoic acid (1), reacts with [Bu4N][ReOCl4] of [Bu4N][ 99gTcOCl4] in EtOH resulting in neutral and stable oxorhenium 2 or oxotechnetium-99 g 3 complexes. Both complexes were characterized by elemental analysis, IR, 1H and 13C NMR spectroscopy. X-ray analysis of 2 showed that the rhenium atom is pentacoordinate presenting a distorted square-pyramidal coordination geometry. The analogous oxotechnetium-99m complex 4 was also prepared quantitatively by the reaction of ligand 1 with Na99mTcO4 in isotonic saline using tin chloride as reducing agent. Its identity was established by chromatographic comparison to the oxorhenium 2 and oxotechnetium 3 complexes. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
