672929-32-7Relevant academic research and scientific papers
Cyrmenins, Novel Antifungal Peptides Containing a Nitrogen-Linked β-Methoxyacrylate Pharmacophore: Isolation and Structural Elucidation
Leibold, Thomas,Sasse, Florenz,Reichenbach, Hans,Hoefle, Gerhard
, p. 431 - 435 (2004)
The novel antifungal metabolites cyrmenin A, B1, and B 2 (1-3) were isolated from Archangium gephyra and Cystobacter armeniaca strains (myxobacteria). The cyrmenins are modified N-acyldipeptide esters containing a didehydroalanine, a 3-O-methyl-didehydroserine and a (2E,4Z)-undecadienoic or -dodecadienoic acid residue. These compounds represent the first bacterial counterparts of strobilurins that are characterized by an α-substituted β-methoxyacrylate pharmacophore. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
