67305-72-0

Basic information

• Product Name: N-(2-mercaptoethyl)propionamide
• Synonyms: N-(2-mercaptoethyl)propionamide;N-(2-Mercaptoethyl)propanamide;beta-Mercaptoethyl propionamide;Einecs 266-638-9;Propanamide, N-(2-mercaptoethyl)-
• CAS NO: 67305-72-0
• Molecular Formula: C₅H₁₁NOS
• Molecular Weight: 133.21194
• EINECS: 266-638-9
• Mol File: 67305-72-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 295.7°Cat760mmHg
• Flash Point: 132.7°C
• Appearance: /
• Density: 1.016g/cm³
• Vapor Pressure: 0.0015mmHg at 25°C
• Refractive Index: 1.472
• CAS DataBase Reference: N-(2-mercaptoethyl)propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-mercaptoethyl)propionamide(67305-72-0)
• EPA Substance Registry System: N-(2-mercaptoethyl)propionamide(67305-72-0)

Safety Data

• Hazardous Substances Data: 67305-72-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H11NOS/c1-2-5(7)6-3-4-8/h8H,2-4H2,1H3,(H,6,7)

Upstream product

• 504-77-8 4,5-dihydro-1,3-oxazol 
• 10431-98-8 2-ethyl-4,5-dihydrooxazole 
• 123-62-6 propionic acid anhydride 
• 60-23-1 Cysteamine 
• 156-57-0 2-mercaptoethylamine hydrochloride 
• 151-56-4 ethyleneimine 
• 1892-31-5 thiopropionic acid 

Downstream Products

• 112394-03-3 N-<2-<<<3-(2-propenyloxy)phenyl>methyl>thio>ethyl>propanamide 
• 112394-00-0 N-<2-<(phenylmethyl)thio>ethyl>-1-propanamine 
• 112394-02-2 N-<2-<<(3-methoxyphenyl)methyl>thio>ethyl>-1-propanamine 
• 112393-97-2 methyl <2-<(phenylmethyl)thio>ethyl>propylcarbamate 
• 112393-94-9 2-phenyl-4-propyl-3-thiomorpholinone 
• 112394-01-1 N-<2-<<<3-(2-propenyloxy)phenyl>methyl>thio>ethyl>-1-propanamine 
• 112393-93-8 2-(3-methoxyphenyl)-4-propylthiomorpholine 
• 112393-99-4 methyl <2-<<<(3-methylphenyl)methyl>thio>ethyl>propyl>carbamate 
• 112393-96-1 2-(3-methoxyphenyl)-4-propyl-3-thiomorpholinone 
• 125698-26-2 N-[2-(2-Phenyl-[1,3]dioxolan-2-ylmethylsulfanyl)-ethyl]-propionamide 
• 125698-27-3 [2-(2-Phenyl-[1,3]dioxolan-2-ylmethylsulfanyl)-ethyl]-propyl-amine 
• 112394-04-4 N-<2-<<(3-methoxyphenyl)methyl>thio>ethyl>propanamide 
• 125698-25-1 N-[2-(2-Oxo-2-phenyl-ethylsulfanyl)-ethyl]-propionamide 

Relevant articles and documents

PROTECTED FUMARIC ACID-BASED METABOLITES FOR THE TREATMENT OF AUTOIMMUNE DISEASES

The present invention provides novel cell-permeable fumarate acyl mercaptoethylamines (FAMs) which have cellular effects including induction of Nrf2 and inhibition of the NFkB pathway. These compounds have utility in medicine including their use in treatment of diseases such as Multiple sclerosis, Non-alcoholic Steatohepatitis, Psoriasis, Inflammatory Arthritis, Inflammatory Bowel Disease, Asthma, Chronic Obstructive Pulmonary Disease, Cancer, Parkinson's Disease, Alzheimer's Disease, Huntington's Disease and Amyotrophic Lateral Sclerosis.

Racemic thioesters for production of polyketides

Facile methods for preparing diketide and triketide thioesters are disclosed. The resulting thioesters may be used as intermediates in the synthesis of desired polyketides, and may contain functional groups which ultimately reside in side chains on the resulting polyketide and thus can be used further to manipulate the polyketide so as form derivatives. The polyketides produced may also be tailored by glycosylation, hydroxylation and the like. New polyketides and their derivatives and tailored forms are thereby produced.

N-(2-mercapto-ethyl)alkanamides from H2 S and 2-H-2-oxazolines or 2-alkyl-2-oxazolines

N-(2-mercaptoethyl)alkanamides are produced by reacting hydrogen sulfide with 2-H-2-oxazolines or 2-alkyl-2-oxazolines. For example, N-(2-mercaptoethyl)acetamide was prepared in excellent yields by incrementally adding 2-methyl-2-oxazoline to a stirred solution of hydrogen sulfide in methanol under autogeneous pressure at about 100° C.