504-77-8

Basic information

• Product Name: 4,5-dihydrooxazole
• Synonyms: 4,5-dihydrooxazole;4,5-dihydro-1,3-oxazole;4,5-dihydro-1,3-oxazol
• CAS NO: 504-77-8
• Molecular Formula: C₃H₅NO
• Molecular Weight: 71.0779
• EINECS: 208-000-4
• Product Categories: Heterocycles
• Mol File: 504-77-8.mol
• Article Data: 63

Chemical Properties

• Melting Point: 168-1720C
• Boiling Point: 74℃
• Flash Point: 5℃
• Appearance: /
• Density: 1.13
• PKA: 4.75±0.50(Predicted)
• CAS DataBase Reference: 4,5-dihydrooxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dihydrooxazole(504-77-8)
• EPA Substance Registry System: 4,5-dihydrooxazole(504-77-8)

Safety Data

• Hazardous Substances Data: 504-77-8(Hazardous Substances Data)

Usage

Chemical Properties

4,5-dihydrooxazole is White Crystalline Solid

Uses

Different sources of media describe the Uses of 504-77-8 differently. You can refer to the following data:
1. Used for the preparation of 2,4-Diaryloxazolines, as insecticides and acaricides.
2. 4,5-dihydrooxazole is used for the preparation of 2,4-Diaryloxazolines, as insecticides and acaricides

InChI:InChI=1/C3H5NO/c1-2-5-3-4-1/h3H,1-2H2

Upstream product

• 24589-68-2 N-(2-chloroethyl)formamide 
• 119072-55-8 tert-butylisonitrile 
• 141-43-5 ethanolamine 
• 693-06-1 (2-hydroxyethyl)-formamide 

Downstream Products

• 492-38-6 2-phenylacrylic acid 
• 288089-62-3 (4S)-4,5-dihydro-4-(1,1-dimethylethyl)-2-phenyloxazole 
• 67305-72-0 1-(2-mercaptoethylamino)-1-propanone 
• 288-42-6 oxazol 
• 30093-97-1 3,4,4-trimethyl-Δ²-oxazolinium iodide 
• 103863-14-5 4-phenyl-3-pyridinecarboxylic acid 
• 130775-90-5 [1S-[1α,2α(Z),3a,4a]]-6-[3-[4-[[(2-Cyclohexylethyl)amino]carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]-4-hexenoic acid, methyl ester 
• 130775-92-7 [1S-[1α,2α(Z),3α,4α]]-6-[3-[4-[[[2-(4-Chlorophenyl)ethyl]amino]carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]-4-hexenoic acid, methyl ester 
• 130776-11-3 [1S-[1α,2α(Z),3α,4α]]-7-[3-[4-[[(4-Cyclohexylbutyl)amino]carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid, methyl ester 

Relevant articles and documents

The dissociation chemistry of low-energy N-formylethanolamine ions: Hydrogen-bridged radical cations as key intermediates

Tandem mass spectrometry experiments show that N-formylethanolamine molecular ions HOCH2CH2NHC(H)O+ (FE1) lose C2H3O, CH2O and H2O to yield m/z 46 ions HC(OH)NH2+, m/z 59 ions CH2N(H)CHOH +, and m/z 71 N-vinylformamide ions CH2C(H)N(H)CHO +. A detailed mechanistic study using the CBS-QB3 model chemistry reveals that the readily generated 1,5-H shift isomer HOCHCH2N(H)C(H) OH+ (FE2) and hydrogen-bridged radical cations (HBRCs) act as key intermediates in a 'McLafferty + 1′ type rearrangement that yields the m/z 46 ions. The co-generated C2H3O neutrals are predicted to be vinyloxy radicals CH2CHO in admixture with CH3CO generated by quid-pro-quo (QPQ) catalysis. A competing C-C bond cleavage in FE1 leads to HBRC [CH2N(H)C(H)O-...H...OCH2] +, which serves as the direct precursor for CH2O loss. In addition, ion FE2 also communicates with a myriad of ion-molecule complexes of vinyl alcohol and formimidic acid whose components may recombine to form distonic ion FE3, HOCH(CH2)N(H)C(H)OH+, which loses H 2O after undergoing a 1,5-H shift. Further support for these proposals comes from experiments with D- and 18O-labelled isotopologues. Previously reported proposals for the H2O and CO losses from protonated N-formylethanolamine are briefly re-examined.

ALPHA-HELIX MIMETIC WITH FUNCTIONALIZED PYRIDAZINE

The synthesis of new α-helix scaffolds mimicking i, i+3 or i+4, i+7 residues, was accomplished. The common pyridazine heterocycle originates from the easily available dimethyl pyridazine-3,6-dicarboxylate building block. These scaffolds may be thought of as synthetic counterparts of amphiphilic α-helices having a hydrophilic face along one side and a hydrophobic face along the other side of the helix.

METHOD OF MAKING UP WITH A LIGHT-SENSITIVE MAKEUP, AND A LIGHT-SENSITIVE MAKEUP COMPOSITION

The present invention provides a method of making up human keratinous material with a light-sensitive makeup, in which: i. a layer of a thermally stable photochromic composition comprising a photochromic agent capable of being developed by UV radiation and an optical agent that screens UV radiation is applied to the keratinous material; and ii. the layer of composition is exposed in non uniform manner to UV radiation to excite the photochromic agent and create a light-sensitive makeup look, the screening power F of the composition as regards solar UV radiation (280 nm to 400 nm) being 2 or more.