67309-37-9

Basic information

• Product Name: 1-PHENYL-2-AMINO-3,3-DIMETHYLBUTANE
• Synonyms: 1-PHENYL-2-AMINO-3,3-DIMETHYLBUTANE
• CAS NO: 67309-37-9
• Molecular Formula: C₁₂H₁₉N
• Molecular Weight: 177.29
• Mol File: 67309-37-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-PHENYL-2-AMINO-3,3-DIMETHYLBUTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-2-AMINO-3,3-DIMETHYLBUTANE(67309-37-9)
• EPA Substance Registry System: 1-PHENYL-2-AMINO-3,3-DIMETHYLBUTANE(67309-37-9)

Safety Data

• Hazardous Substances Data: 67309-37-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 5338, 1986 DOI: 10.1021/jo00376a053

Upstream product

• 160204-29-5 C₂₉H₂₉N₄P 
• 160204-28-4 1-(1-azido-2,2-dimethylpropyl)benzotriazole 
• 630-19-3 pivalaldehyde 
• 111098-60-3 1-(benzotriazol-1-yl)-1-chloro-2,2-dimethylpropane 
• 61860-99-9 N-(2,2-dimethylpropylidene)-N-(1,1,1-trimethylsilyl)amine 
• 100-39-0 benzyl bromide 
• 630-18-2 tert-butyl isocyanide 
• 6921-34-2 benzylmagnesium chloride 
• 160204-34-2 C₃₀H₃₂NP 

Relevant articles and documents

Convenient Access to Primary Amines by Employing the Barbier-Type Reaction of N-(Trimethylsilyl)imines Derived from Aromatic and Aliphatic Aldehydes

A new versatile preparation of primary amines via benzylation of aromatic and aliphatic aldimines is described. Sonochemical and traditional methods for generation of the reactive intermediates are compared and contrasted. Competitive reactions were analyzed via free energy relationships to support the proposed alkylative mechanism.

Tandem Alkylation-Reduction of Nitriles. Synthesis of Branched Primary Amines

Tandem alkylation-reduction of a series of nitriles by alkylating with Grignard reagents followed by reducing with lithium-ammonia afforded the corresponding branched primary amines in reasonable isolated yields.Alkyl and aromating nitriles and a variety of Grignard reagents have been employed in this convenient procedure.A mechanism for the reduction of the imine intermediate is suggested.