67337-01-3Relevant academic research and scientific papers
Synthesis of L-dioxolane nucleosides and related chemistry
Liang,Lee,Newton,Chu
, p. 1546 - 1553 (2007/10/02)
(+)-L- or (+)-(2R,4S)-1-[4-(hydroxymethyl)-1,3-dioxolan-2-yl]-5-fluorouracil (25) and other novel classes of 1,3-dioxolane nucleosides have been synthesized. Coupling of 2-methoxy-4-[[(tert-butyldiphenylsilyl)oxy]methyl]-1,3-dioxolane (23) or 2-methyl-1,3
Reactions of Some Pyranoside Diol Monotriflates with Nucleophiles and Bases
Knapp, Spencer,Naughton, Andrew B. J.,Jaramillo, Carlos,Pipik, Brenda
, p. 7328 - 7334 (2007/10/02)
Reaction of pyranoside diol (equatorial) monotriflates with soft, nonbasic nucleophiles is a useful way to make axial heteroatom-substituted and "epimerized" pyranosides, particularly where a fused acetal ring inhibits ring contraction.Among the substrates examined (1,2,3,4,35), only 4 shows a strong tendency to give ring-contracted products.The reaction of 1-3 with more basic nucleophiles (F(1-), t-BuO(1-)) leads to the anhydrosugars 8, 25, and 26, respectively.The SN2 reaction of 35 with tetra n-butylammonium iodide forms the basis for a new synthesis of the Cerny epoxide 32.
Bausteine von Oligosacchariden, XXII. Synthese der Trisaccharid-Sequenz α-D-GlcNAc-(1-4)-β-D-Gal-(1-4)-D-GlcNAc aus blutgruppenaktiven Substanzen
Paulsen, Hans,Schnell, Dagmar
, p. 333 - 345 (2007/10/02)
A directly stereoselective α-glycoside synthesis to oligosaccharides succeeds in the presence of AgClO4/Ag2CO3 in methylene chloride with the α-bromide 1 of 2-azido-2-desoxy-D-glucose.By reaction with 1 the disaccharides 3, 7a, 7b, 18 and the trisaccharid
