67337-73-9

Basic information

• Product Name: Nsc55330
• Synonyms: Nsc55330
• CAS NO: 67337-73-9
• Molecular Formula: C₇H₁₂N₂O₂
• Molecular Weight: 156.18238
• Mol File: 67337-73-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 208°C
• Boiling Point: 280.42°C (rough estimate)
• Flash Point: °C
• Appearance: /
• Density: 1.1832 (rough estimate)
• Refractive Index: 1.4880 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 8.91±0.10(Predicted)
• Water Solubility: 1.937g/L(temperature not stated)
• CAS DataBase Reference: Nsc55330(CAS DataBase Reference)
• NIST Chemistry Reference: Nsc55330(67337-73-9)
• EPA Substance Registry System: Nsc55330(67337-73-9)

Safety Data

• Hazardous Substances Data: 67337-73-9(Hazardous Substances Data)

Usage

General Description

Nsc55330, also known as 1,4-Dioxane, is a clear, colorless liquid that is commonly used as a solvent in various industrial processes including in the production of adhesives, varnishes, and paints. It is also used as a stabilizer in the manufacturing of certain products such as soaps and detergents. Nsc55330 has been classified as a probable human carcinogen by the Environmental Protection Agency (EPA) and is considered to be harmful to the environment. It is known to be toxic if ingested or inhaled, and prolonged exposure to this chemical has been linked to adverse health effects such as liver and kidney damage. Due to its potential risks, efforts are being made to limit its use and to find safer alternatives.

Upstream product

• 861543-08-0 N-ethoxycarbonyl-DL-leucine amide 
• 54129-53-2 isovaleraldehyde cyanohydrin 
• 57-13-6 urea 
• 61-90-5 L-leucine 
• 506-87-6 ammonium carbonate 
• 72177-82-3 α-isobutyl-α-aminoacetonitrile hydrochloride 
• 590-28-3 potassium cyanate 
• 2508-63-6 DL-leucine hydrochloride 
• 151-50-8 potassium cyanide 
• 590-86-3 isovaleraldehyde 
• 13079-20-4 2-Amino-4-methyl-pentanoic acid amide 

Downstream Products

• 212332-01-9 5-Isobutyl-3-phenylsulfanylmethyl-imidazolidine-2,4-dione 
• 2221-06-9 5-isobutyl-3-phenylimidazolidine-2,4-dione 
• 61-90-5 L-leucine 
• 328-38-1 (R)-leucine 

Relevant articles and documents

A one-pot synthesis of 5,5-disubstituted hydantoin derivatives using magnetic Fe3O4 nanoparticles as a reusable heterogeneous catalyst

A facile and rapid method for the one-pot synthesis of 5,5-disubstituted hydantoins in the presence of magnetic Fe3O4 nanoparticles has been developed. The multicomponent reactions of carbonyl compounds (aldehydes and ketones), potassium cyanide and ammonium carbonate were carried out under solvent-free conditions to obtain various hydantoin derivatives. The magnetic catalyst could be readily separated by an external magnet from the reaction mixture. This procedure has many advantages, such as the use of a reusable magnetic catalyst, high yields, short reaction times, simplicity and very easiness with implementing the methodology.

Preparation of α-aminothioamides from aldehydes

The conversion of aldehydes into α-aminonitriles and thence into imidazolidin-4-thiones has been studied.Hydrolysis of the appropriate imidazolidin-4-thiones gave thioamides of nine naturally occuring α-amino acids.The possible pre-biotic significance of these compounds is discussed.