673478-92-7

Basic information

• Product Name: {(2R,4S,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-iodomethyl-tetrahydro-furan-2-yloxy}-tert-butyl-dimethyl-silane
• CAS NO: 673478-92-7
• Molecular Weight: 674.691
• Mol File: 673478-92-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(2R,4S,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-iodomethyl-tetrahydro-furan-2-yloxy}-tert-butyl-dimethyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: {(2R,4S,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-iodomethyl-tetrahydro-furan-2-yloxy}-tert-butyl-dimethyl-silane(673478-92-7)
• EPA Substance Registry System: {(2R,4S,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-iodomethyl-tetrahydro-furan-2-yloxy}-tert-butyl-dimethyl-silane(673478-92-7)

Safety Data

• Hazardous Substances Data: 673478-92-7(Hazardous Substances Data)

Upstream product

• 252667-55-3 (S)-5-(4,4'-dimethoxytrityloxymethyl)-5H-furan-2-one 
• 673478-88-1 5'-O-(4,4'-dimethoxytrityl)-3'-iodomethyl-2'-deoxy-D-ribonolactone 
• 673478-86-9 5'-O-(4,4'-dimethoxytrityl)-3'-hydroxymethyl-2'-deoxy-D-ribonolactone 
• 78508-96-0 (5S)-5-(hydroxymethyl)-5H-furan-2-one 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 673478-97-2 (2S,4S,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-iodomethyl-tetrahydro-furan-2-ol 

Relevant articles and documents

Synthetic studies towards a novel, chemical stable, abasic site analogue of DNA

We synthesized the phosphinate 7 via photoaddition of methanol to the α,β unsaturated deoxyribono lactone as the key step, followed by an Arbusov reaction for the introduction of phosphorous. Precursor 7 serves for the synthesis and incorporation into DNA