67367-26-4

Basic information

• Product Name: METHYL 2-METHOXYNICOTINATE
• Synonyms: METHYL 2-METHOXYNICOTINATE;Methyl 2-methoxypyridine-3-carboxylate;2-Methoxy-nicotinic acid Methyl ester;METHYL 2-METHOXYNICOTITE
• CAS NO: 67367-26-4
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16
• Mol File: 67367-26-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 114-115 °C(Press: 12 Torr)
• Appearance: /
• Density: 1.156±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 1.36±0.10(Predicted)
• CAS DataBase Reference: METHYL 2-METHOXYNICOTINATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-METHOXYNICOTINATE(67367-26-4)
• EPA Substance Registry System: METHYL 2-METHOXYNICOTINATE(67367-26-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 67367-26-4(Hazardous Substances Data)

Usage

General Description

Methyl 2-methoxynicotinate, also known as methyl 2-methoxy-3-pyridinecarboxylate, is a chemical compound with the molecular formula C8H9NO3. It is a ester derivative of nicotinic acid and is commonly used in the synthesis of pharmaceuticals and agrochemicals. Methyl 2-methoxynicotinate is known for its potential as an anti-inflammatory agent and can also be used in the treatment of neurological disorders. It is a colorless to pale yellow liquid with a fruity scent and is often used as a flavoring agent in the food and beverage industry. Additionally, this compound has been found to have antioxidant properties, making it a promising candidate for use in skincare and cosmetic products.

Upstream product

• 67-56-1 methanol 
• 35905-85-2 2-bromonicotinic acid 
• 93-60-7 methyl 3-pyridinecarboxylate 

Downstream Products

• 1083168-93-7 methyl 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxylate 
• 1246765-27-4 methyl 2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate 
• 884502-27-6 C₁₇H₁₂BrNO₄ 
• 884502-26-5 C₁₇H₁₃NO₄ 
• 884501-05-7 4-(4-oxo-4H-pyrano[2,3-b]pyridine-2-yl)phenyl acetate 
• 884500-82-7 2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridine-4-one 
• 884500-75-8 2-(3-fluoro-4-hydroxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one 
• 884500-72-5 2-(4-hydroxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one 
• 122262-38-8 2,2-dimethyl-2,3-dihydropyrano<2,3-b>pyridin-4-one 

Relevant articles and documents

Synthesis of 9,9′-Spirobifluorenes and 4,5-Diaza-9,9′-spirobifluorenes and Their Application as Affinity Materials for Quartz Crystal Microbalances

Two different classes of aza analogues of 9,9′-spirobifluorenes have been synthesized. These were obtained by either furnishing the spirobifluorene with additional pyridyl moieties or by installing the aza function directly into the spirobifluorene core. These structurally rigid compounds were then evaluated as affinity materials for quartz crystal microbalances and proved to be highly potent for the detection of volatile organic compounds.

MULTIPLE PATHS FOR PHOTOALKYLATION OF PYRIDINECARBOXYLIC ESTERS IN ALCOHOLS

Photochemical substitution of ring hydrogen of pyridinecarboxylic esters by alkyl groups derived from solvent alcohols occurs in several paths: 1) alkylation initiated by excited carbonyl moiety of the ester group and 2) alkylation initiated by the excitation of the ?-electronic system of the pyridine ring.In the photoreaction of methyl 3-pyridinecarboxylate in acidic methanol, three types of excited state (two triplet states for alkylation and a singlet state for alkoxylation) contribute simultaneously.