67428-17-5

Upstream product

• 178960-10-6 (S)-1-(1-cyclohex-1-enyl)ethyl acetate 
• 61111-62-4 potassium salt of dimethyl malonate 
• 55591-27-0 1-(cyclohex-1-en-1-yl)eth-1-yl acetate 
• 18424-76-5 sodiodimethylmalonate 
• 90087-64-2 1-(1-nitroethyl)cyclohexene 
• 108-59-8 malonic acid dimethyl ester 

Relevant academic research and scientific papers

Regio- and stereoselectivity control in palladium-catalyzed allylic alkylation of 1-cycloalkenylmethyl acetates

Enantiomerically pure allylic acetates 1a and 1b were obtained by lipase-catalyzed acylation through kinetic resolution processes of the racemates. Palladium-catalyzed alkylation of 1a with dimethyl malonate was both regio- and stereoselective, showing th

Palladium-Catalyzed Substitutions of Allylic Nitro Compounds. Regiochemistry

Primary, secondary, and tertiary allylic nitro compounds underwent Pd(0)-catalyzed allylic substitution by stabilized carboanions, secondary amines, and benzenesulfinate ion (PhSO2-). α,β-disubstituted α-nitro olefins also behaved as allylic nitro compounds, via base-catalyzed vinyl -> allyl rearrangement, and underwent allylic substitution by secondary amines and PhSO2-.The regiochemistry of these substitutions was dependent on the structure of the allylic nitro compound amd on the steric bulk of the nucleophile.Generally, substitution occurred at the lesshindered or least substituted site.In some cases added or generated NaNO2 affected the regioselectivity of the allylic substitution of allylic nitro compounds and some allylic acetates by PhSO2-.Under these conditions, the more sterically hindered allylic sulfones were formed.