Cyclohexene, 1-(bromomethyl)-2,4,4-trimethyl-

Base Information

Chemical Name:Cyclohexene, 1-(bromomethyl)-2,4,4-trimethyl-
CAS No.:67451-72-3
Molecular Formula:C10H17Br
Molecular Weight:217.149
Hs Code.:
DSSTox Substance ID:DTXSID40448447
Nikkaji Number:J956.074B
Wikidata:Q82267435

Synonyms:Cyclohexene, 1-(bromomethyl)-2,4,4-trimethyl-;67451-72-3;DTXSID40448447;1-(Bromomethyl)-2,4,4-trimethyl-1-cyclohexene

Suppliers and Price of Cyclohexene, 1-(bromomethyl)-2,4,4-trimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Cyclohexene, 1-(bromomethyl)-2,4,4-trimethyl-

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:1
Exact Mass:216.05136
Heavy Atom Count:11
Complexity:177

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(CCC(C1)(C)C)CBr

Technology Process of Cyclohexene, 1-(bromomethyl)-2,4,4-trimethyl-

There total 10 articles about Cyclohexene, 1-(bromomethyl)-2,4,4-trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 103985-40-6
(2,4,4-trimethyl-1-cyclohexen-1-yl)methanol

: 67451-72-3
1-(bromomethyl)-2,4,4-trimethyl-1-cyclohexene

Guidance literature:: With pyridine; phosphorus tribromide; In diethyl ether; at -78 - 20 ℃; for 1.5h; Inert atmosphere;
DOI:10.3998/ark.5550190.0013.323

Reference yield:

: 814-78-8,25988-32-3
3-Methyl-3-buten-2-one

: 67451-72-3
1-(bromomethyl)-2,4,4-trimethyl-1-cyclohexene

Guidance literature:: Multi-step reaction with 5 steps

1: N-benzyl-trimethylammonium hydroxide / tert-butyl alcohol / 2.5 h / 60 °C

2: palladium 10% on activated carbon; hydrogen / diethyl ether / 16 h / 20 °C

3: sodium hydride / mineral oil; dimethyl sulfoxide / 24 h / 20 °C

4: pyridine; trifluorormethanesulfonic acid / tetrahydrofuran / 1.5 h / 40 °C

5: pyridine; phosphorus tribromide / diethyl ether / 2.5 h / -78 - 20 °C

With pyridine; trifluorormethanesulfonic acid; palladium 10% on activated carbon; hydrogen; phosphorus tribromide; N-benzyl-trimethylammonium hydroxide; sodium hydride; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide; mineral oil; tert-butyl alcohol; 1: |Robinson Annulation / 3: |Corey-Tschaikosky Epoxidation;
DOI:10.1021/acs.orglett.9b02601

Reference yield:

: 4,6,6-trimethyl-1-oxaspiro[2.5]octane

: 67451-72-3
1-(bromomethyl)-2,4,4-trimethyl-1-cyclohexene

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; trifluorormethanesulfonic acid / tetrahydrofuran / 1.5 h / 40 °C

2: pyridine; phosphorus tribromide / diethyl ether / 2.5 h / -78 - 20 °C

With pyridine; trifluorormethanesulfonic acid; phosphorus tribromide; In tetrahydrofuran; diethyl ether;
DOI:10.1021/acs.orglett.9b02601