67456-91-1

Basic information

• Product Name: Benzoic acid, 2-[(1E)-2-phenylethenyl]-, ethyl ester
• CAS NO: 67456-91-1
• Molecular Formula: C17H16O2
• Molecular Weight: 252.313
• Mol File: 67456-91-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[(1E)-2-phenylethenyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[(1E)-2-phenylethenyl]-, ethyl ester(67456-91-1)
• EPA Substance Registry System: Benzoic acid, 2-[(1E)-2-phenylethenyl]-, ethyl ester(67456-91-1)

Safety Data

• Hazardous Substances Data: 67456-91-1(Hazardous Substances Data)

Upstream product

• 74-96-4 ethyl bromide 
• 60901-21-5 o-styrylbenzoic acid 
• 88-67-5 2-Iodobenzoic acid 
• 100-42-5 styrene 
• 1829-28-3 ethyl 2-iodobenzoate 
• 6091-64-1 2-bromobenzoic acid ethyl ester 
• 201230-82-2 carbon monoxide 
• 110166-71-7 ethyl 2-(phenylethynyl)benzoate 
• 5079-90-3 (E)-2-styrylbenzoic acid 

Downstream Products

• 103-30-0 (E)-1,2-diphenyl-ethene 

Relevant articles and documents

Design and chemical synthesis of root gravitropism inhibitors: Bridged analogues of ku-76 have more potent activity

Previously, we found (2Z,4E)-5-phenylpenta-2,4-dienoic acid (ku-76) to be a selective inhibitor of root gravitropic bending of lettuce radicles at 5 μM, with no concomitant growth inhibition, and revealed the structure–activity relationship in this inhibitory activity. The conformation of ku-76 is flexible owing to the open-chain structure of pentan-2,4-dienoic acid with freely rotating single bonds, and the (2Z)-alkene moiety may be isomerized by external factors. To develop more potent inhibitors and obtain insight into the target biomolecules, various analogues of ku-76, fixed through conformation and/or configuration, were synthesized and evaluated. Stereochemical fixation was effective in improving the potency of gravitropic bending inhibition. Finally, we found highly potent conformational and/or configurational analogues (ku-257, ku-294 and ku-308), that did not inhibit root growth. The inhibition of root curvature by these analogues was comparable to that of naptalam.

Synthesis, modeling studies and evaluation of E-stilbene hydrazides as potent anticancer agents

A group of new thermodynamically more stable E-2-styrylbenzohydrazide derivatives (5a-i) were synthesized via palladium catalyzed Mizoroki-Heck reaction conditions. All synthesized compounds were characterized by UV-visible, FT-IR, 1H NMR, sup

Synthesis of E-stilbene azomethines as potent antimicrobial and antioxidant agents

A series of new extensively conjugated E -stilbene azomethines (5a–5h) were synthesized and screened for their antioxidant and antimicrobial activity. The compounds were tested against bacterial (Escherichia coli, Staphylococcus aureus, Klebsiella pneumon