67468-61-5

Upstream product

• 100-97-0 hexamethylenetetramine 
• 778-22-3 2,2-diphenylpropane 
• 281-27-6 1-aza-adamantane 
• 76-05-1 trifluoroacetic acid 
• 80-05-7 BPA 
• 74-89-5 methylamine 

Downstream Products

• 150253-68-2 N-[4-(1-Methyl-1-phenylethyl)benzyl]-methylamine 
• 216755-38-3 N-(3-bromo-5-methylbenzyl)-N-methyl-[4-(1-methyl-1-phenylethyl)benzyl]amine 

Relevant academic research and scientific papers

EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF

The present invention relates to compounds of formula I or pharmaceutically acceptable salt, solvate or hydrate thereof wherein ASC is -N(R8)ASC-1; ASC-1 is C 2-C 5alkylene-N(R9a)R9b or C(=O)-C 1-C 4alkylene-N(R

OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE

Compounds, compositions, and methods for treating C. difficile are provided.

New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof

New tertiary 8-hydroxyquinoline-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof are disclosed. These compounds are useful as antifungal agents. Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis. These compounds are also active against Candida species such as Candida Albicans and Candida Glabrata.

NEW TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF

New tertiary 8-hydroxyquinoiine-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof are disclosed. These compounds are useful as antifungal agents. Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis. These compounds are also active against Candida species such as Candida Albicans and Candida Glabrata.

Amine derivatives

The present invention relates to amine derivatives represented by formula (1) or salts thereof. R3represents C1-C3 alkyl, hydroxylated C1-C5 alkyl, C1-C5 acyl; C2-C5 alkenyl, or a halogen atom; and k, l, and m are each an integer of 1 to 4.) Exhibiting excellent antifungal effect, these compounds are highly useful as antifungal agents, antifungal compositions, drugs, etc.

Antifungal amine derivatives and processing for producing the same

Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. [in the formula (1, R1represents a C1-5alkyl group which may be halogenated, R2represents 4-(1,1-dimethylalkyl)benzyl group, 4-(1-methyl-phenylethyl)benzyl group, 1-or 2-naphthylmethyl group, or a hydrocarbon group having 3,3-dimethyl-1-butynyl group or a phenyl group at its terminal and 1 to 3 double bonds; R3represents oxygen atom or a methylene group which may be substituted by a C1-4alkyl group; and R4represents 1-or 2 naphthyl group or a phenyl group which may be substituted.

Synthesis and structure-activity relationships of phenyl-substituted benzylamine antimycotics: A novel benzylbenzylamine antifungal agent for systemic treatment

Derivatives of the benzylamine antimycotics with an extra phenyl ring incorporated in the side chain have been prepared and their antifungal activity evaluated. The potency is strongly dependent on the distance between the two phenyl groups and the type o