67468-81-9

Basic information

• Product Name: Ethanone, 1-[4-(1,1-dimethylpropyl)phenyl]-
• CAS NO: 67468-81-9
• Molecular Formula: C13H18O
• Molecular Weight: 190.285
• Mol File: 67468-81-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-(1,1-dimethylpropyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(1,1-dimethylpropyl)phenyl]-(67468-81-9)
• EPA Substance Registry System: Ethanone, 1-[4-(1,1-dimethylpropyl)phenyl]-(67468-81-9)

Safety Data

• Hazardous Substances Data: 67468-81-9(Hazardous Substances Data)

Upstream product

• 2049-95-8 tery-amylbenzene 
• 75-36-5 acetyl chloride 
• 99-90-1 para-bromoacetophenone 
• 594-39-8 2-methyl-2-butylamine 

Downstream Products

• 20129-71-9 4-tert-pentyl-benzoic acid 
• 1130-58-1 1-(1,1-Dimethylpropyl)-4-ethylbenzol 
• 26114-14-7 (4-tert-pentyl-phenyl)-acetic acid 

Relevant articles and documents

Dual Nickel/Photoredox-Catalyzed Deaminative Cross-Coupling of Sterically Hindered Primary Amines

We report a method to activate α-3° amines for deaminative arylation via condensation with an electron-rich aldehyde and merge this reactivity with nickel metallaphotoredox to generate benzylic quaternary centers, a common motif in pharmaceuticals and natural products. The reaction is accelerated by added ammonium salts. Evidence is provided in support of two roles for the additive: inhibition of nickel black formation and acceleration of the overall reaction rate. We demonstrate a robust scope of amine and haloarene coupling partners and show an expedited synthesis of ALK2 inhibitors.