674792-07-5

Basic information

• Product Name: 1-BOC-2,2-DIMETHYL-PIPERAZINE
• Synonyms: 2,2-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT BUTYL-ESTER;1-BOC-2,2-DIMETHYL-PIPERAZINE;tert-Butyl 2,2-dimethylpiperazine-1-carboxylate;1-Piperazinecarboxylic acid, 2,2-dimethyl-, 1,1-dimethylethyl ester;4-tert-Butoxycarbonyl-3,3-dimethylpiperazine;1-boc-2,2-diMethylpiperazine hcl;1-boc-2,2-diMethylpiperazine hydrochloride;EOS-62182
• CAS NO: 674792-07-5
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.3
• Mol File: 674792-07-5.mol

Chemical Properties

• Boiling Point: 275.1 °C at 760 mmHg
• Flash Point: 120.2 °C
• Appearance: /
• Density: 0.977 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.53±0.40(Predicted)
• CAS DataBase Reference: 1-BOC-2,2-DIMETHYL-PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-2,2-DIMETHYL-PIPERAZINE(674792-07-5)
• EPA Substance Registry System: 1-BOC-2,2-DIMETHYL-PIPERAZINE(674792-07-5)

Safety Data

• Hazardous Substances Data: 674792-07-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Manufacturing:
1-Boc-2,2-dimethyl-piperazine is used as a building block for the synthesis of various pharmaceutical compounds. Its Boc protecting group and dimethyl structure contribute to the creation of complex molecules with potential therapeutic applications.
Used in Organic Synthesis:
1-Boc-2,2-dimethyl-piperazine is used as a reagent in organic synthesis, where its Boc protecting group and dimethyl structure facilitate the formation of diverse organic molecules. 1-Boc-2,2-dimethyl-piperazine serves as a key intermediate in the preparation of a wide range of chemical products.

InChI:InChI=1S/C11H22N2O2/c1-10(2,3)15-9(14)13-7-6-12-8-11(13,4)5/h12H,6-8H2,1-5H3

Upstream product

• 84477-72-5 2,2-dimethylpiperazine 

Downstream Products

• 223786-44-5 tert-butyl 2,2-dimethyl-4-(4-nitrophenyl)piperazine-1-carboxylate 
• 223786-45-6 4-(4-amino-phenyl)-2,2-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 850628-95-4 4-[4-(8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)phenyl]-2,2-dimethylpiperazine-1-carboxylic acid tert-butyl ester 
• 1124215-20-8 tert-butyl 4-(4-amino-3-fluorobenzoyl)-2,2-dimethylpiperazine-1-carboxylate 
• 1354947-68-4 1,1-dimethylethyl 2,2-dimethyl-4-({1-[4-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl)-1-piperazinecarboxylate 
• 1355004-04-4 1,2,2-trimethyl-4-({1-[3-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl)piperazine 
• 1354947-62-8 3,3-dimethyl-1-({1-[3-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl)piperazine 
• 1354947-61-7 1,1-dimethylethyl 2,2-dimethyl-4-({1-[3-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl)-1-piperazinecarboxylate 
• 1392888-96-8 C₂₃H₃₀N₈S 
• 1429181-92-9 tert-butyl 4-(4-((S)-1-(4-((S)-4-isopropyl-2-oxooxazolidin-3-yl)pyrimidin-2-ylamino)ethyl)benzyl)-2,2-dimethylpiperazine-1-carboxylate 
• 1449580-95-3 4-[4-(4-(ethoxycarbonyl)-1,3-oxazol-5-yl)phenyl]-2,2-dimethylpiperazine-1-carboxylic acid tert-butyl ester 
• 1460030-77-6 tert-butyl 2,2-dimethyl-4-[[4-(morpholin-4-yl)-2-(trifluoromethyl)phenyl]methyl]piperazine-1-carboxylate 
• 1460030-92-5 4-[4-[(3,3-dimethylpiperazin-1-yl)methyl]-3-(trifluoromethoxy)phenyl]morpholine 
• 1460030-83-4 2,5-dioxopyrrolidin-1-yl 2,2-dimethyl-4-{[4-(morpholin-4-yl)-2-(trifluromethoxy)phenyl]methyl}piperazine-1-carboxylate 

Relevant articles and documents

CDK INHIBITORS AND USES THEREOF

The present disclosure provides compounds and compositions that are CDK inhibitors selective for CDK4 and/or CDK6, and methods of use thereof.

PIPERAZINE UREA DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS

Certain novel piperazine urea derivatives are agonists of the human melanocortin-4 receptor (MC-4R) and, in particular, are receptor-subtype selective agonists of MC-4R. They are useful for the treatment, control, or prevention of diseases and disorders r