674793-08-9

Upstream product

• 108-24-7 acetic anhydride 
• 674793-04-5 Acetic acid (1R,4S,6S,7R,8S,10S,11R)-11-acetoxy-8-(3-benzyl-ureido)-6-methoxy-11-methyl-3-oxo-2,5-dioxa-tricyclo[5.4.0.0^4,8]undec-10-yl ester 
• 674793-30-7 Acetic acid (1R,4S,6S,7R,8S,10S,11R)-11-acetoxy-6-methoxy-11-methyl-3-oxo-8-(2,2,2-trichloro-acetylamino)-2,5-dioxa-tricyclo[5.4.0.0^4,8]undec-10-yl ester 
• 674793-01-2 Acetic acid (1R,4S,5S,7S,8R,9S)-9-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4,8-dihydroxy-8-methyl-3-oxo-5-(2,2,2-trichloro-acetylamino)-2-oxa-bicyclo[3.3.1]non-7-yl ester 
• 674793-27-2 Trichloro-acetic acid (1R,4S,5R)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-5-(2,2,2-trichloro-acetylamino)-5-vinyl-cyclohex-2-enyl ester 
• 674793-02-3 Acetic acid (1R,4S,6S,7R,8S,10S,11R)-11-hydroxy-6-methoxy-11-methyl-3-oxo-8-(2,2,2-trichloro-acetylamino)-2,5-dioxa-tricyclo[5.4.0.0^4,8]undec-10-yl ester 
• 457643-81-1 2,2,2-Trichloro-N-[(1S,2S,3R,5R,6R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-hydroxy-6-methyl-3-vinyl-7-oxa-bicyclo[4.1.0]hept-3-yl]-acetamide 
• 457643-80-0 2,2,2-Trichloro-N-[(1R,2S,5R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-hydroxy-4-methyl-1-vinyl-cyclohex-3-enyl]-acetamide 
• 457643-79-7 (1R,5R,6S)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-8-methyl-3-trichloromethyl-5-vinyl-2-oxa-4-aza-bicyclo[3.3.1]nona-3,7-diene 
• 674793-26-1 (1R,4S,5R)-5-Amino-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-5-vinyl-cyclohex-2-enol 
• 253674-40-7 2,2,2-Trichloro-N-[(1R,2S,4S,5S)-4,5-dibromo-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-1-vinyl-cyclohexyl]-acetamide 
• 162089-64-7 (1S,6S,1'S)-trichloro-N-[1-vinyl-4-methyl-6-(3',3'-dimethyl-2',4'-dioxolanyl)-cyclohex-3-enyl]acetamide 

Relevant academic research and scientific papers

Stereocontrolled Synthesis of 8,11-Dideoxytetrodotoxin, An Unnatural Analogue of Puffer Fish Toxin

8,11-Dideoxytetrodotoxin, an unnatural tetrodotoxin analogue, was synthesized in a highly stereoselective manner from a common intermediate from our synthetic studies on tetrodotoxin. The key features in the synthesis were as follows: neighboring group pa