67502-70-9

Upstream product

• 530-48-3 1,1-Diphenylethylene 
• 1666-13-3 diphenyl diselenide 
• 24946-01-8 1,1-diphenyl-2-(phenylseleno)-ethan-1-ol 
• 13610-02-1 1-phenoxy-2-propyne 
• 92496-20-3 (3-phenoxyprop-1-yn-1‐yl)benzene 
• 7677-24-9 trimethylsilyl cyanide 
• 98-80-6 phenylboronic acid 
• 33757-48-1 N-quinolin-8-yl-benzamide 
• 645-96-5 Benzeneselenol 
• 19997-66-1 1-iodo-2,2-diphenylethylene 
• 26189-62-8 phenyl 2,2-diphenylethenyl sulfone 
• 119-61-9 benzophenone 
• 67502-51-6 diethyl [(phenylselanyl)methyl]phosphonate 
• 16054-93-6 2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one 

Relevant academic research and scientific papers

Selenium Radical Mediated Cascade Cyclization: Concise Synthesis of Selenated Benzofurans (Benzothiophenes)

Presented in this work is a novel methodology for the synthesis of selenated benzofurans (or benzothiophenes) via AgNO2-catalyzed radical cyclization of 2-alkynylanisoles (or 2-alkynylthioanisoles), Se powder, and arylboronic acids. This method

[Bis(trifluoroacetoxy)iodo]benzene Mediated C-3 Selenylation of Pyrido[1,2-a]Pyrimidin-4-Ones Under Ambient Conditions

Herein, we report the [Bis(trifluoroacetoxy)iodo]benzene mediated C?H bond arylselenylation of 4H-Pyrido-[1,2-a]-Pyrimidin-4-ones using readily available organodiselenides. This methodology is scalable and permits for the generation of a broad spectrum of functionally and structurally diverse selenoether derivatives in very promising yields (up to 98%). Notably, this protocol proceeds at ambient conditions and in the absence of a metal. The application of this methodology for the facile synthesis of ArSe substituted 5H-thiazolo-pyrido[3,2-a]pyrimidin-4-ones is also demonstrated. (Figure presented.).

Metal free C-3 chalcogenation (sulfenylation and selenylation) of 4H-pyrido[1,2-a]pyrimidin-4-ones

An expeditious metal free C-3 chalcogenation of 4H-pyrido[1,2-a]pyrimidin-4-one has been devised to synthesize diversely orchestrated 3-ArS/ArSe derivatives in high yields (up to 95%). This operationally simple reaction proceeds under mild reaction condit

Metal-Free Synthesis of Aryl Selenocyanates and Selenaheterocycles with Elemental Selenium

This work reports a green method for the synthesis of aryl selenocyanates via a three-component reaction of arylboronic acids, Se powder, and trimethylsilyl cyanide (TMSCN) under metal-free and additive-free conditions. Remarkably, TMSCN acts as not only the substrate, but also the catalyst. Various selenaheterocycles can be also accessed with a catalytic amount of TMSCN.

Cu-Catalyzed Radical Selenylation of Olefin: A Direct Access to Vinyl Selenides

A method for the synthesis of vinyl selenides via Cu-catalyzed three-component reactions of arylboronic acids, Se powder and diarylethylenes has been developed. The reaction proceeds via addition of in situ generated selenium-centered radical to carbon-carbon double bond. This method highlights the use of easily accessible Se powder as selenium source in the construction of vinyl selenides for the first time. (Figure presented.).

Metal-free regioselective C-H chalcogenylation of coumarins/(hetero)arenes at ambient temperature

A novel, practical and metal-free approach for the regioselective selenation of coumarins employing (bis(trifluoroacetoxy)iodo)benzene (PIFA) at room temperature is presented. The developed method is suitable for a wide substrate scope and affords 3-selen

Method for synthesizing alpha,beta-unsaturated selenium compound

The invention belongs to the field of organic selenium chemistry, and particularly relates to a method for synthesizing an alpha,beta-unsaturated selenium compound. The compound is synthesized by using an aryl boronic acid compound, elemental selenium and a diarylethene compound as reaction substrates. The method avoids toxic selenium-mercury reagents and toxic selenide reagents, conforms to the modern green development concept, and provides a green and economical method for synthesizing unsaturated selenium compounds in the future.

Organo-selenium mediated regio- and stereoselective iodoselenylation of alkynes in an aqueous medium: Simple access to (: E)-β-iodoalkenyl selenides

A method for the simple and efficient iodoselenylation of simple alkynes under mild conditions using commercially available molecular iodine (I2) and diorganoyldiselenides as starting materials has been developed. A broad range of alkynes can b

Diphenyl-Diselenide-Mediated Domino Claisen-Type Rearrangement/Cyclization of Propargylic Aryl Ethers: Synthesis of Naphthofuran-2-carboxaldehyde Derivatives

A diphenyl-diselenide-mediated Claisen-type rearrangement/cyclization of propargylic aryl ethers under metal-free conditions is developed, affording various naphthofuran-2-carboxaldehydes in moderate to excellent yield. The broad substrate scope and excel

Synthesis of 3-Organoselenyl-2H-Coumarins from Propargylic Aryl Ethers via Oxidative Radical Cyclization

A metal-free oxidative radical cyclization/selenylation of propargylic aryl ethers with diaryl diselenides was developed. This protocol provided an alternative method to synthesize 3-organoselenyl-2H-coumarins via the formation of C?Se bond, C?C bond, and C=O bond in one step. Moreover, a broad range of functional groups (such as halogen, aldehyde, ketone, cyano, and nitro group) were tolerated. (Figure presented.).