67560-74-1

Upstream product

• 23316-68-9 (2R,3R,4R,5R)-3,4-bis(benzoyloxy)-5-((benzoyloxy)methyl)tetrahydrofuran-2-carboxylic acid 
• 23316-67-8 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl-1-carbonitrile 
• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 

Downstream Products

• 105350-95-6 3,4,6-Tri-O-benzoyl-2,5-anhydro-D-allonoylthiosemicarbazide 
• 129149-83-3 (4S,trans)-4-(benzoyloxy)-5-<(benzoyloxy)methyl>-N-(cyanocarbethoxymethyl)-4,6-dihydrofuran-2-carboxamide 
• 129149-81-1 ethyl 2-<(3',4',6'-tri-O-benzoyl-2',5'-anhydroallonyl)amino>-2-cyanoacetate 
• 491876-52-9 C₃₄H₂₈N₂O₇ 
• 105350-98-9 2-Amino-5-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-1,3,4-oxadiazole 
• 105350-97-8 2-Amino-5-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-1,3,4-thiadiazole 
• 69244-25-3 isotiazofurin 
• 129149-85-5 ethyl 5-amino-2-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)oxazole-4-carboxylate 
• 129149-87-7 ethyl 2-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)oxazole-4-carboxylate 
• 129149-86-6 ethyl 5-amino-2-<5'-<(benzoyloxy)methyl>furan-2'-yl>oxazole-4-carboxylate 
• 129173-94-0 ethyl 2-<5'-<(benzoyloxy)methyl>furan-2'-yl>oxazole-4-carboxylate 
• 129149-89-9 Oxazofurin 
• 144987-56-4 C₃₀H₂₄N₄O₇S 
• 144987-58-6 C₃₀H₂₆N₄O₇S 

Relevant academic research and scientific papers

Improved synthesis and preparative scale resolution of racemic monastrol

The Yb(OTf)3 catalyzed Biginelli cyclocondensation reaction of 3-hydroxybenzaldehyde, ethyl acetoacetate and thiourea afforded the corresponding dihydropyrimidine-2-thione, called monastrol, in 95% isolated yield. The chiral resolution of racem

Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP

The synthesis of a series of novel C-linked nucleotide triphosphates is reported. These exhibit excellent agonist potency and selectivity for the P2Y2 receptor with a number of examples having EC50 values below 10 nM. Representative compounds from the N-linked and C-linked series showed enhanced metabolic stability compared with that of the natural ligand UTP.

Synthesis of 1-chloroacetyl-1-dehydroxy-2,3,5-tri-O-benzoyl-β-D-ribofuranose. A potentially versatile intermediate for the synthesis of C-nucleosides

New key carbohydrate intermediate, 1-chloroacetyl-1-dehydroxy-2,3,5-tri-O-benzoyl-β-D-ribofuranose (1a) has been synthesized. The application of this key intermediate would be very wide. We have very conveniently synthesized several C-nucleosides includin

C-Nucleosides. Part 1. Preparation of Tiazofurin and N-Substituted Tiazofurins from Benzyl(2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)penicillinate

The title penicillinate (11a)-assembled from 2,5-anhydro-3,4,6-tri-O-benzoyl-D-allonic acid (12e) and benzyl 6β-aminopenicillinate (13a)-has been transformed into tiazofurin (6a), N-tiazofurin (6c), and N-(1-methoxyca

SYNTHESIS OF 2-AMINO-5-β-D-RIBOFURANOSYL-1,3,4-THIADIAZOLE AND 2-AMINO-β-D-RIBOFURANOSYL-1,3,4-OXADIAZOLE

Benzoylated 2-amino-5-ribosylthiadiazole III and 2-amino-5-oxadiazole IV were synthesized by cyclization of allonoylthiosemicarbazide I and allonoylsemicarbazide II with phosphorus pentoxide in nitromethane.The oxadiazole IV was alternatively prepared by