676591-83-6Relevant academic research and scientific papers
Synthesis of disubstituted ynamides from β,β-dichloroenamides and electrophiles
Rodríguez, David,Martínez-Esperón, M. Fernanda,Castedo, Luis,Saá, Carlos
, p. 1963 - 1965 (2007)
Treatment of β,β-dichloroenamides with n-butyllithium, followed by addition of an electrophile, provides disubstituted ynamides in far greater yield than direct functionalization of terminal ynamides. Georg Thieme Verlag Stuttgart.
Synthesis of Oxindoles through the gold-catalyzed oxidation of N-arylynamides
Yang, Liu-Qing,Wang, Kai-Bing,Li, Chuan-Ying
, p. 2775 - 2779 (2013/06/27)
α-Oxo gold carbenoids generated by the oxidation of N-arylynamides can be trapped intramolecularly at the ortho position of the aryl ring to give functionalized oxindoles under mild reaction conditions. Pyridine N-oxide works as the oxidant, ligand, and base in this transformation. Copyright
Intermolecular and selective synthesis of 2,4,5-trisubstituted oxazoles by a gold-catalyzed formal [3+2] cycloaddition
Davies, Paul W.,Cremonesi, Alex,Dumitrescu, Lidia
supporting information; experimental part, p. 8931 - 8935 (2011/10/19)
Oxazole new world: A gold-catalyzed intermolecular reaction of pyridine-N-aminides with ynamides can be used to prepare trisubstituted 1,3-oxazoles with a variety of functional groups. This formal [3+2] cycloaddition employs robust conjugated N-ylides as
Coupling and cycloaddition of ynamides: Homo- and Negishi coupling of tosylynamides and intramolecular [4 + 2] cycloaddition of N-(o-ethynyl)phenyl ynamides and arylynamides
Martínez-Esperón, María Fernanda,Rodríguez, David,Castedo, Luis,Saá, Carlos
, p. 3843 - 3855 (2007/10/03)
N,N′-aryl- and N,N′-alkyl-buta-1,3-diyne-1,4-ditosylamides have been synthesized for the first time, in good to excellent yields, by copper-catalyzed dimerization of the corresponding N-aryl or N-alkyl tosylynamides. Negishi coupling of N-ethynylzinc tosy
Homocoupling of 1-Alkynyl Tosylamides
Rodri?guez, David,Castedo, Luis,Saa?, Carlos
, p. 377 - 379 (2007/10/03)
N,N′-substituted-buta-1,3-diyne-1,4-tosylamides have been synthesized for the first time, in good to excellent yields, via copper-catalyzed dimerization of the corresponding 1-alkynyltosylamides.
