676596-61-5 Usage
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 676596-61-5 differently. You can refer to the following data:
1. A synthetic intermediate for the synthesis of 1-Azakenpaullone and other Kenpaullone derivatives.
2. A synthetic intermediate for the synthesis of 1-Azakenpaullone and other Kenpaullone
Check Digit Verification of cas no
The CAS Registry Mumber 676596-61-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,6,5,9 and 6 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 676596-61:
(8*6)+(7*7)+(6*6)+(5*5)+(4*9)+(3*6)+(2*6)+(1*1)=225
225 % 10 = 5
So 676596-61-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N2O5/c1-3-20-12(18)8-7-11(17)16-10-6-5-9-15-13(10)14(19)21-4-2/h5-6,9H,3-4,7-8H2,1-2H3,(H,16,17)
676596-61-5Relevant articles and documents
9-Cyano-1-azapaullone (Cazpaullone), a Glycogen Synthase Kinase-3 (GSK-3) inhibitor activating pancreatic β cell protection and replication
Stukenbrock, Hendrik,Mussmann, Rainer,Geese, Marcus,Ferandin, Yoan,Lozach, Olivier,Lemcke, Thomas,Kegel, Simone,Lomow, Alexander,Burk, Ulrike,Dohrmann, Cord,Meijer, Laurent,Austen, Matthias,Kunick, Conrad
, p. 2196 - 2207 (2008/12/22)
Recently, the serine/threonine kinase glycogen synthase kinase-3 (GSK-3) emerged as a regulator of pancreatic β cell growth and survival. On the basis of the previous observation that GSK-3 inhibitors like 1-azakenpaullone promote β cell protection and re