676596-63-7

Basic information

• Product Name: 5H-Pyrido[3,2-b]azepine-6,9-(7H,8H)-dione
• Synonyms: 5H-Pyrido[3,2-b]azepine-6,9-(7H,8H)-dione
• CAS NO: 676596-63-7
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.17202
• Product Categories: Aromatics;Heterocycles;Intermediates
• Mol File: 676596-63-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 433.8±40.0 °C(Predicted)
• Appearance: /
• Density: 1.292±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 12.79±0.20(Predicted)
• CAS DataBase Reference: 5H-Pyrido[3,2-b]azepine-6,9-(7H,8H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Pyrido[3,2-b]azepine-6,9-(7H,8H)-dione(676596-63-7)
• EPA Substance Registry System: 5H-Pyrido[3,2-b]azepine-6,9-(7H,8H)-dione(676596-63-7)

Safety Data

• Hazardous Substances Data: 676596-63-7(Hazardous Substances Data)

Upstream product

• 676596-61-5 3-(3-ethoxycarbonyl-propionylamino)-pyridine-2-carboxylic acid ethyl ester 
• 676596-62-6 9-hydroxy-6-oxo-6,7-dihydro-5H-pyrido[3,2-b]azepine-8-carboxylic acid ethyl ester 
• 27507-15-9 ethyl 3-aminopyridine-2-carboxylate 

Downstream Products

• 914088-78-1 7,8-dihydro-5H-pyrido[3,2-b]azepine-6,9-dione 9-{[4-(trifluoromethyl)phenyl]hydrazone} 
• 914088-80-5 7,8-dihydro-5H-pyrido[3,2-b]azepine-6,9-dione 9-[(4-iodophenyl)hydrazone] 
• 1019995-21-1 C₁₅H₁₂F₂N₄O 
• 914088-68-9 7,8-dihydro-5H-pyrido[3,2-b]azepine-6,9-dione 9-[(3,5-dichlorophenyl)hydrazone] 
• 1019995-38-0 C₂₂H₁₇N₃O 
• 914088-66-7 7,8-dihydro-5H-pyrido[3,2-b]azepine-6,9-dione 9-[(4-chlorophenyl)hydrazone] 
• 1019995-39-1 C₂₁H₁₅N₃O 
• 676596-64-8 9-[(4-bromo-phenyl)-hydrazono]-5,7,8,9-tetrahydro-pyrido[3,2-b]azepin-6-one 
• 914088-63-4 4-[2-(6-oxo-5,6,7,8-tetrahydro-9H-pyrido[3,2-b]azepine-9-ylidene)hydrazino]benzonitrile 
• 1019995-22-2 3-iodo-4-[2-(6-oxo-5,6,7,8-tetrahydro-9H-pyrido[3,2-b]azepine-9-ylidene)hydrazino]benzonitrile 
• 914088-61-2 4-[2-(6-oxo-5,6,7,8-tetrahydro-9H-pyrido[3,2-b]azepin-9-ylidene)hydrazino]benzoic acid 
• 914088-75-8 7,8-dihydro-5H-pyrido[3,2-b]azepine-6,9-dione 9-(phenylhydrazone) 
• 914088-71-4 7,8-dihydro-5H-pyrido[3,2-b]azepine-6,9-dione 9-[(4-fluorophenyl)hydrazone] 

Relevant articles and documents

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Recently, the serine/threonine kinase glycogen synthase kinase-3 (GSK-3) emerged as a regulator of pancreatic β cell growth and survival. On the basis of the previous observation that GSK-3 inhibitors like 1-azakenpaullone promote β cell protection and re