676596-82-0

Upstream product

• 22255-22-7 3,5,4'-trimethoxy-trans-stilbene 
• 123-11-5 4-methoxy-benzaldehyde 
• 268550-11-4 diethyl 2-bromo-3,5-dimethoxybenzyl phosphonate 
• 34132-25-7 2-bromo-1-(bromomethyl)-3,5-dimethoxybenzene 

Downstream Products

• 1001258-87-2 (E)-[2,4-dimethoxy-6-(4-methoxystyryl)phenyl]-(3,5-dimethoxyphenyl)methanol 
• 1133711-37-1 1-(3,5-dimethoxyphenyl)-5,7-dimethoxy-2-(4-methoxyphenyl)-1H-indene 
• 885263-37-6 4,6-dimethoxy-3-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)-1H-inden-1-one 

Relevant academic research and scientific papers

RESVERATROL-BASED COMPOUNDS

The invention provides a compound having the structure compound having the structure: Formula wherein bond a is present or absent, wherein when bond a is absent, then bond β is: Sign (I) and R1 is: Formula and when bond a is present, then Rsub

Total syntheses of hopeanol and hopeahainol a empowered by a chiral br?nsted acid induced pinacol rearrangement

Rearranging complexity: The total synthesis of resveratrol dimers hopeanol (1) and hopeahainolA (2, see scheme) is described. By using a reagent-driven pinacol rearrangement coupled with specific oxidation chemistry, the frameworks are constructed concisely and on scale. Moreover, the route has biogenetic implications that trace the origin of these compounds to more common dimeric family members. Copyright

SYNTHESIS OF RESVERATROL-BASED NATURAL PRODUCTS

Processes for synthesizing reveratrol-based oligomers are provided. In addition, reservatrol-based oligomer compounds free of plant extract are provided.

Total synthesis of diverse carbogenic complexity within the resveratrol class from a common building block

Although biomimetic approaches have proven capable of converting resveratrol (1) concurrently into many of the more complex oligomers produced by plants throughout the world (such as 2-10), methods to access single members of the family have proven far more difficult to identify. Herein is described a strategy-level solution based on the use of a common building block, one distinct from Nature's starting material, that can participate in a variety of highly selective, reagent-controlled reaction cascades. These endeavors have led to the controlled synthesis of 25 natural products and analogues, molecules whose architectures encompass nearlyall the carbogenic diversity of the resveratrol family.

Total synthesis of resveratrol-based natural products: A chemoselective solution

Despite the attention paid to resveratrol (1) owing to its potent biological activity, little effort has been devoted to studying resveratrol-based oligomers (such as 2-4). The first general synthetic approach is outlined for accessing the carbogenic diversity possessed by this family of compounds. (Chemical Equation Presented).

Syntheses and radical scavenging activities of resveratrol derivatives

Nine new resveratrol derivatives, having bromo, iodo, and fluoroethyl groups, were designed and synthesized. All compounds having free phenol groups showed good free radical scavenging activity. Among them, 2-bromoresveratrol 19 has a similar free radical scavenging activity to (+)-catechin.