67715-17-7

Upstream product

• 141-78-6 ethyl acetate 
• 81968-55-0 1-[(S)-2-(2-Methoxy-phenyl)-hexahydro-pyrrolo[1,2-c]imidazol-3-yl]-propan-1-one 
• 81968-54-9 1-[(S)-2-(2-Methoxy-phenyl)-hexahydro-pyrrolo[1,2-c]imidazol-3-yl]-ethanone 
• 80657-59-6 1-[(S)-2-(2-Methoxy-phenyl)-hexahydro-pyrrolo[1,2-c]imidazol-3-yl]-2-methyl-propan-1-one 
• 81968-53-8 [(S)-2-(2-Methoxy-phenyl)-hexahydro-pyrrolo[1,2-c]imidazol-3-yl]-phenyl-methanone 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 6893-26-1 D-Glutamic acid 
• 90-04-0 2-methoxy-phenylamine 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 

Downstream Products

• 1621189-36-3 2-(2-methoxyphenyl)-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c]imidazol-2-ium hexafluorophosphate 

Relevant academic research and scientific papers

Chiral azo-heterocyclic carbene precursor compound with bicyclic framework and preparation method thereof

The invention discloses a chiral azo-heterocyclic carbene precursor compound with a bicyclic framework and a preparation method thereof. A series of the chiral azo-heterocyclic carbene precursor compound with the bicyclic framework is obtained by taking c

Modular synthesis of new bicyclic carbene precursors

A series of new N-heterocyclic carbene (NHC) precursors, containing bicyclic pyrrolo[1,2-c]imidazole framework, were prepared from N-(tert-butoxycarbonyl)-L-proline (1-Boc-L-proline). The sequential attachment of nitrogen nucleophiles and subsequent ring

Synthesis and characterization of new chiral azolinium salts, precursors to N-heterocyclic carbenes, derived from l-proline

A short and flexible procedure for the preparation of seven chiral azolinium and five functionalized chiral azolinium salts, precursors to N-heterocyclic carbenes, derived from l-proline has been developed. Moderate to good overall yields were obtained. Some NHC dimers and thiones were isolated. X-ray crystal structure determinations of two [Rh-NHC] complexes were also reported.

Enantioselective rhodium catalyzed hydroboration of olefins using chiral bis(aminophosphine) ligands

The synthesis of new chiral bis(aminophosphine) ligands 1-5 was achieved and assessed in the enantioselective rhodium catalyzed hydroboration of various olefins with catecholborane. Enantioselectivities up to 77% were obtained.

AN ASYMMETRIC SYNTHESIS OF β-FORMYL β-HYDROXY ESTERS

Optically active β-formyl β-hydroxy esters are prepared in high enantiomeric excess by treating 2-acyl-1,3-diazabicyclo-octane derivatives, prepared from (S)-2-(substituted aminomethyl)-pyrrolidine and phenylglyoxal monohydrate or methyl hydroxymethoxyacetate, with metal enolates of ethyl acetate.