67715-55-3Relevant academic research and scientific papers
Synthesis of the napalilactone and pathylactone A spirocyclic skeleton
Vyvyan, James R.,Rubens, Courtney A.,Halfen, Jason A.
, p. 221 - 224 (2002)
The spirolactone core of napalilactone and pathylactone A was synthesized in five steps from 2-methyl-2-cyclohexen-1-one or 2,3-dimethyl-2-cyclohexen-1-one. This spirolactone contains all of the carbon atoms and three of the four stereocenters of napalilactone and pathylactone A.
Reactions of Trialkylsilyl Trifluoromethanesulfonates, I. - Synthesis of Trialkylsilyl Enol Ethers
Emde, Herbert,Goetz, Andreas,Hofmann, Karin,Simchen, Gerhard
, p. 1643 - 1657 (2007/10/02)
The reactions of the ketones 2,2-bromoketones 6, α,β-unsaturated ketones 8, 1,2-diketones, and aliphatic aldehydes 20 with trialkylsilyl triflates 1 in the presence of triethylamine (4) at room temperature yield the silyl enol ethers 3, 7, 9, 11, and 21.The silylation of the unsymmetrical ketones 12 with 1a/4 runs regioselectively in the thermodynamical sense using 1a/12 in excess and yields the enol ethers 13t.The course of this reaction is discussed briefly.
