677325-05-2Relevant academic research and scientific papers
Model Studies and First Synthesis of the Antifungal and Antibacterial Agent Cladobotryal
Clive, Derrick L. J.,Huang, Xiaojun
, p. 1872 - 1879 (2007/10/03)
The antifungal and antibacterial agent cladobotryal (1) was synthesized by a convergent route from lactone 31 and aldehyde 13, a key step in the elaboration of the pyridinone ring being conversion of a Boc group on nitrogen into a CO2SiPr-i3 group. The simple model compounds 9 and 10, representing the core of cladobotryal and of 5, respectively, were prepared as support studies for making the natural product.
