127087-63-2

Upstream product

• 62247-39-6 3-Hydroxy-2-phenyl-1-aminopropane 
• 100-42-5 styrene 
• 1211383-27-5 methyl 3-((tert-butoxycarbonyl)amino)-2-phenylpropanoate 
• 618094-94-3 2-[3-[(tert-butyldimethylsilanyl)oxy]-2-phenylpropyl]isoindole-2,3-dione 
• 677324-99-1 3-((tert-butyldimethylsilyl)oxy)-2-phenylpropan-1-amine 
• 173423-55-7 3-((tert-butyldimethylsilyl)oxy)-2-phenylpropan-1-ol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 127087-62-1 (3-hydroxy-2-phenylpropyl)carbamic acid tert-butyl ester 
• 677325-00-7 [3-[(tert-butyldimethylsilanyl)oxy]-2-phenylpropyl]carbamic acid tert-butyl ester 

Downstream Products

• 1211383-29-7 methyl 1-({3-[(tert-butoxycarbonyl)amino]-2-phenylpropyl}amino)yclopentanecarboxylate 
• 67098-56-0 DL-N-(t-butoxycarbonyl)-2-phenyl-β-alanine 
• 677325-05-2 hexahydro-4-oxo-5-phenyl-3a,5-bis(phenylselanyl)furo[2,3-b]pyridine-7-carboxylic acid tert-butyl ester 
• 677325-02-9 [3-hydroxy-3-(tetrahydro-2-hydroxyfuran-3-yl)-2-phenylpropyl]carbamic acid tert-butyl ester 
• 677325-04-1 hexahydro-4-oxo-5-phenylfuro[2,3-b]pyridine-7-carboxylic acid tert-butyl ester 
• 677325-03-0 hexahydro-4-hydroxy-5-phenylfuro[2,3-b]pyridine-7-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Copper-catalyzed borylative aminomethylation of C-C double and triple bonds withN,O-acetal

A copper-catalyzed borylaminomethylation of multiple carbon-carbon bonds withN,O-acetal and bis(pinacolato)diboron has been disclosed that offers efficient and expedient access to γ-amino boronates. The products contain a valuable amine and boronate, whic

3- AND 6-QUINOLINES WITH N-ATTACHED HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS

Compounds of Formula (I): (where variables R1A, R1B, R2, R3, R4, A, and Z are as defined herein) which are useful as antagonists of CGRP receptors, and useful in the treatment or prevention of disease

Model Studies and First Synthesis of the Antifungal and Antibacterial Agent Cladobotryal

The antifungal and antibacterial agent cladobotryal (1) was synthesized by a convergent route from lactone 31 and aldehyde 13, a key step in the elaboration of the pyridinone ring being conversion of a Boc group on nitrogen into a CO2SiPr-i3 group. The simple model compounds 9 and 10, representing the core of cladobotryal and of 5, respectively, were prepared as support studies for making the natural product.

First synthesis of the antifungal and antibacterial agent cladobotryal

The antifungal and antibacterial agent cladobotryal (1) was synthesized by a convergent route from lactone 5 and aldehyde 12, a key step in the elaboration of the pyridinone ring being conversion of a t-BuOC(O) group on nitrogen into an i-Pr3SiOC(O) group.