677350-80-0

Basic information

• Product Name: Benzenamine, N-(4-fluorophenyl)-3-methyl-
• CAS NO: 677350-80-0
• Molecular Formula: C13H12FN
• Molecular Weight: 201.243
• Mol File: 677350-80-0.mol

Chemical Properties

• CAS DataBase Reference: Benzenamine, N-(4-fluorophenyl)-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N-(4-fluorophenyl)-3-methyl-(677350-80-0)
• EPA Substance Registry System: Benzenamine, N-(4-fluorophenyl)-3-methyl-(677350-80-0)

Safety Data

• Hazardous Substances Data: 677350-80-0(Hazardous Substances Data)

Upstream product

• 32578-31-7 3-tolyl triflate 
• 371-40-4 4-fluoroaniline 
• 1765-93-1 4-fluoroboronic acid 
• 108-44-1 1-amino-3-methylbenzene 

Relevant articles and documents

N-(Pyridin-2-yl)benzamide: Efficient ligand for the nickel catalyzed Chan-Lam cross-coupling reaction

An efficient protocol for the Chan-Lam cross-coupling reactions of arylboronic acids with aryl or alkyl amines has been developed by employing simple N-(pyridin-2-yl)benzamide ligand with Ni(OAc)2·4H2O in the presence of TMG base. The reaction proceeded well with high yields by employing various N-nucleophiles at low catalytic loadings.

Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds

Mitotic kinesin spindle protein (KSP) is involved in the assembly of the bipolar spindle during cell division. On the basis of a common 2,3-fused indole substructure within the complex frameworks of terpendole E and other KSP inhibitors, the carbazoles with a bulky alkyl group were identified as a novel KSP inhibitory scaffold. Additionally, among several naturally occurring cell growth inhibitors with 2,3-fused indole structures,β-carboline alkaloids, harman and harmine, showed moderate inhibition of KSP.