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Benzamide, N-(1-amino-2,2,2-trichloroethyl)-, also known as 2,2,2-trichloro-N-(1-aminoethyl)acetamide, is an organic compound with the chemical formula C4H7Cl3NO. It is a derivative of benzamide, featuring a 1-amino-2,2,2-trichloroethyl group attached to the nitrogen atom. Benzamide, N-(1-amino-2,2,2-trichloroethyl)- is characterized by its potential reactivity due to the presence of the amino group and the trichloroethyl moiety, which may undergo various chemical transformations. It is important to note that the compound's properties, such as its reactivity, solubility, and potential applications, are influenced by the presence of these functional groups. The compound may be of interest in chemical research and synthesis, particularly in the development of new pharmaceuticals or agrochemicals, given its unique structure and the possibility of forming stable derivatives. However, due to the presence of multiple chlorine atoms, it is also essential to consider its environmental impact and safety profile.

6776-62-1

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6776-62-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6776-62-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,7 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6776-62:
(6*6)+(5*7)+(4*7)+(3*6)+(2*6)+(1*2)=131
131 % 10 = 1
So 6776-62-1 is a valid CAS Registry Number.

6776-62-1Relevant academic research and scientific papers

Structure-activity relationship studies of salubrinal lead to its active biotinylated derivative

Long, Kai,Boyce, Michael,Lin, He,Yuan, Junying,Ma, Dawei

, p. 3849 - 3852 (2007/10/03)

The synthesis and structure-activity relationships (SAR) of salubrinal, a small molecule that protects cells from apoptosis induced by endoplasmic reticulum (ER) stress, are described. It is revealed that the trichloromethyl group greatly contributes to the activity. Based on the SAR results, salubrinal was converted into a biotinylated derivative which retains activity and can be used as a biological tool for target identification.

Potassium channel openers

-

, (2008/06/13)

Compounds of formula I: are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

Synthesis and X-ray molecular structure of N-(1-amino-2,2-dichloroethyl)benzamides

Guirado, Antonio,Andreu, Raquel,Zapata, Andrés,Cerezo, Alfredo,Bautista, Delia

, p. 5087 - 5092 (2007/10/03)

Efficient procedures for the synthesis of N-(1-alkylamino-2,2-dichloroethyl)benzamides, N-(1-arylamino-2,2-dichloroethyl)benzamides and N-(1-amino-2,2-dichloroethyl)benzamides are reported. These compounds are of special interest as intermediates to acces

Potassium channel openers

-

, (2008/06/13)

Compounds of formula I: are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

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