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N-(2,2,2-trichloro-1-hydroxyethyl)benzamide is a chemical compound with the molecular formula C8H7Cl3NO2. It is a derivative of benzamide, where the hydroxyethyl group is substituted with three chlorine atoms. N-(2,2,2-trichloro-1-hydroxyethyl)benzamide is known for its potential use as a herbicide, specifically for controlling broadleaf and grassy weeds. It works by inhibiting the enzyme enolpyruvylshikimate-3-phosphate synthase (EPSPS), which is a key component in the biosynthesis of aromatic amino acids in plants. The trichloro-hydroxyethyl group in the molecule is responsible for its herbicidal activity, as it can penetrate plant tissues and disrupt essential metabolic processes, leading to the death of the plant. Due to its effectiveness and selectivity, N-(2,2,2-trichloro-1-hydroxyethyl)benzamide is an important tool in agricultural management, helping to protect crops from weed competition and ensuring higher yields.

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  • 6316-07-0 Structure
  • Basic information

    1. Product Name: N-(2,2,2-trichloro-1-hydroxyethyl)benzamide
    2. Synonyms: benzamide, N-(2,2,2-trichloro-1-hydroxyethyl)-
    3. CAS NO:6316-07-0
    4. Molecular Formula: C9H8Cl3NO2
    5. Molecular Weight: 268.5243
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 6316-07-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 414.3°C at 760 mmHg
    3. Flash Point: 204.4°C
    4. Appearance: N/A
    5. Density: 1.505g/cm3
    6. Vapor Pressure: 1.32E-07mmHg at 25°C
    7. Refractive Index: 1.593
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: N-(2,2,2-trichloro-1-hydroxyethyl)benzamide(CAS DataBase Reference)
    11. NIST Chemistry Reference: N-(2,2,2-trichloro-1-hydroxyethyl)benzamide(6316-07-0)
    12. EPA Substance Registry System: N-(2,2,2-trichloro-1-hydroxyethyl)benzamide(6316-07-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 6316-07-0(Hazardous Substances Data)

6316-07-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6316-07-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,1 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6316-07:
(6*6)+(5*3)+(4*1)+(3*6)+(2*0)+(1*7)=80
80 % 10 = 0
So 6316-07-0 is a valid CAS Registry Number.

6316-07-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2,2,2-trichloro-1-hydroxyethyl)benzamide

1.2 Other means of identification

Product number -
Other names Chloral-benzamid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6316-07-0 SDS

6316-07-0Relevant articles and documents

Synthesis of New 1Н-Pyrrolo[3,4-с]pyridine-1,3(2Н)-diones

Klyuchko,Chumachenko,Shablykin,Brovarets

, p. 348 - 356 (2021/04/26)

Abstract: A method for the synthesis of a series of new substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones was proposed based on the Diels–Alder type reaction of 4-methoxy-1,3-oxazoles with maleimide derivatives.

Novel 2H-1,3-benzoxazine ring formation by intramolecular heterocyclization of N-(α-aryloxyalkyl)imidoyl chlorides

Onys'ko, Petro P.,Zamulko, Kateryna A.,Kyselyova, Olena I.,Syzonenko, Yaroslav A.

, p. 421 - 428 (2017/12/18)

A convenient synthetic approach to derivatives of 2-trichloromethyl and 2-dichlorometylene-2H-1,3-benzoxazines, based on intramolecular heterocyclization of readily accessible N-(α-aryloxytrichloroethyl)imidoyl chlorides, was developed. Base induced dehyd

A facile synthesis of 1,3-thiazole-4-sulfonyl chlorides

Demydchuk, Bogdan A.,Kondratyuk, Kostyantyn M.,Korniyenko, Andrey N.,Brovarets, Vladimir S.,Vasylyshyn, Roman Y.,Tolmachev, Andrey,Lukin, Oleg

experimental part, p. 2866 - 2875 (2012/07/16)

(Chemical Equation Presented) A four-step preparative-scale synthesis of eight 2-alkyl- and arylsubstituted thiazole-4-sulfonyl chlorides from chloralamides is reported. Good yields and easy availability of starting materials are valuable advantages of the procedure that gives access to formerly unattainable building blocks. Copyright Taylor & Francis Group, LLC.

Structure-activity relationship studies of salubrinal lead to its active biotinylated derivative

Long, Kai,Boyce, Michael,Lin, He,Yuan, Junying,Ma, Dawei

, p. 3849 - 3852 (2007/10/03)

The synthesis and structure-activity relationships (SAR) of salubrinal, a small molecule that protects cells from apoptosis induced by endoplasmic reticulum (ER) stress, are described. It is revealed that the trichloromethyl group greatly contributes to the activity. Based on the SAR results, salubrinal was converted into a biotinylated derivative which retains activity and can be used as a biological tool for target identification.

Sml2-mediated facile syntheses of N(2,2-dichlorovinyl)amides from acetates of chloralamide

Li, Jian,Wang, Xiaoxia,Zhang, Yongmin

, p. 738 - 739 (2007/10/03)

Samarium diiodide-mediated elimination reaction provides a simple and general method to synthesise N-(2, 2-dichlorovinyl)amides 4 from acetates of chloralamides 3 in excellent yields. This novel reaction proceeds readily within a few minutes at room tempe

Potassium channel openers

-

, (2008/06/13)

Compounds of formula I: are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

Potassium channel openers

-

, (2008/06/13)

Compounds of formula I: are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

Synthesis of α-(acylamino)polyhaloalkylphosphoryl compounds by the reaction of trivalent phosphorus chlorides with N-(α-hydroxypolyhaloalkyl)amides

Onys'ko

, p. 1763 - 1767 (2007/10/03)

N-(α-Hydroxypolyhaloalkyl)amides react with trivalent phosphorus chlorides to give α-(acylamino)polyhaloalkylphosphoryl compounds via phosphorotropic rearrangement of intermediate phosphites or phosphinites.

REACTION OF N,N-DICHLOROAMIDES WITH TRICHLOROETHYLENE

Mirskova, A. N.,Levkovskaya, G. G.,Gogoberidze, I. T.,Kalikhman, I. D.,Voronkov, M. G.

, p. 239 - 241 (2007/10/02)

The reaction of N,N-dichloroacetamide and N,N-dichlorobenzamide with trichloroethylene in an inert atmosphere leads to the formation of the products from the transformation of the corresponding acylimines of chloral, i.e. 2,2,2-trichloro-1,1-di(acetamido)benzamido ethanes, N-(2,2,2-trichloro-1-hydroxyethyl)acetamides and the corresponding benzamides, and pentachloroethane.In the reaction of N,N-dichlorobenzamide with trichloroethylene in the presence of atmospheric oxygen N-(dichloroacetyl)benzamide is obtained in additon to N-(2,2,2-trichloro-1-hydroxyethyl)benzamide and pentachloroethane.Its formation results from the parallel processes of oxidation of the trichloroethylene to dichloroacetyl chloride and reduction of the dichlorobenzamide to benzamide and their reaction.

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