677702-22-6 Usage
Description
5-IODO-1H-INDAZOLE-3-CARBOXYLIC ACID is a chemical compound that belongs to the class of indazole derivatives. It is characterized by a 5-iodo-1H-indazole core structure with a carboxylic acid functional group at the 3-position. This carboxylic acid compound has potential applications in medicinal chemistry due to its various biological activities, such as antiviral, antifungal, and antimicrobial properties. Furthermore, it serves as a starting material for the synthesis of other indazole-based compounds and is utilized as a reagent in organic synthesis for the preparation of pharmaceuticals and agrochemicals.
Uses
Used in Medicinal Chemistry:
5-IODO-1H-INDAZOLE-3-CARBOXYLIC ACID is used as a biologically active compound for its antiviral, antifungal, and antimicrobial properties, making it a valuable component in the development of new medications to combat various infections and diseases.
Used in Synthesis of Indazole-based Compounds:
As a starting material, 5-IODO-1H-INDAZOLE-3-CARBOXYLIC ACID is used in the synthesis of other indazole-based compounds, which can have diverse applications in pharmaceuticals, agrochemicals, and other chemical industries.
Used in Organic Synthesis for Pharmaceutical Preparation:
5-IODO-1H-INDAZOLE-3-CARBOXYLIC ACID is used as a reagent in organic synthesis processes, specifically for the preparation of pharmaceuticals, where its unique structure and functional group contribute to the creation of new drug molecules.
Used in Organic Synthesis for Agrochemical Preparation:
Similarly, in the agrochemical industry, 5-IODO-1H-INDAZOLE-3-CARBOXYLIC ACID is utilized as a reagent in organic synthesis for the development of new agrochemical products, potentially enhancing crop protection and yield.
Check Digit Verification of cas no
The CAS Registry Mumber 677702-22-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,7,7,0 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 677702-22:
(8*6)+(7*7)+(6*7)+(5*7)+(4*0)+(3*2)+(2*2)+(1*2)=186
186 % 10 = 6
So 677702-22-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H5IN2O/c9-5-1-2-7-6(3-5)8(4-12)11-10-7/h1-4H,(H,10,11)
677702-22-6Relevant articles and documents
An optimized procedure for direct access to 1: H -indazole-3-carboxaldehyde derivatives by nitrosation of indoles
Chevalier, Arnaud,Ouahrouch, Abdelaaziz,Arnaud, Alexandre,Gallavardin, Thibault,Franck, Xavier
, p. 13121 - 13128 (2018/04/23)
Indazole derivatives are currently drawing more and more attention in medicinal chemistry as kinase inhibitors. 1H-indazole-3-carboxaldehydes are key intermediates to access to a variety of polyfunctionalized 3-substituted indazoles. We report here a general access to this motif, based on the nitrosation of indoles in a slightly acidic environment. These very mild conditions allow the conversion of both electron-rich and electron-deficient indoles into 1H-indazole-3-carboxaldehydes.
DIHYDROPYRIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS
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Page/Page column 51, (2008/12/06)
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INDAZOLECARBOXAMIDE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF MALARIA
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Page/Page column 10, (2010/11/28)
The invention relates to methods of treating or preventing malaria which comprises administering to a patient in need thereof, an effective amount of a 1H-indazole-3-carboxamide derivative of general formula (I), in the form of a base or of an addition salt with an acid, or in the form of a hydrate or of a solvate of said base or acid addition salt.
