677725-68-7

Upstream product

• 500214-38-0 4-chloro-[1,3]dioxolo[4,5-g]cinnoline 
• 28657-75-2 2-amino-4,5-methylenedioxy-acetophenone 
• 61203-48-3 2-iodo-4,5-dimethoxybenzoic acid 
• 934-98-5 2-(4-methylpiperazin-1-yl)ethylamine 
• 113258-92-7 4,5-dimethoxy-2-iodobenzoyl chloride 
• 677725-67-6 1-[2-[N-(6,7-methylenedioxycinnolin-4-yl)]amino]ethyl-4-methylpiperazine 

Relevant academic research and scientific papers

11H-Isoquino[4,3-c]cinnolin-12-ones: Novel anticancer agents with potent topoisomerase I-targeting activity and cytotoxicity

Recent studies have identified 2,3-dimethoxy-8,9-methylenedioxy-11-[(2- dimethylamino)ethyl]-11H-isoquino[4,3-c]cinnolin-12-one (1a) as a novel topoisomerase I-targeting agent with potent cytotoxic activity. The effect of varied substituents at the 11-pos