67820-83-1

Basic information

• Product Name: 6-CHLORO-4-METHYL-3-PHENYL-PYRIDAZINE
• Synonyms: AURORA KA-554;6-CHLORO-4-METHYL-3-PHENYL-PYRIDAZINE
• CAS NO: 67820-83-1
• Molecular Formula: C₁₁H₉ClN₂
• Molecular Weight: 204.66
• Mol File: 67820-83-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 364.9 °C at 760 mmHg
• Flash Point: 205.9 °C
• Appearance: /
• Density: 1.208 g/cm³
• Vapor Pressure: 3.43E-05mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 6-CHLORO-4-METHYL-3-PHENYL-PYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-4-METHYL-3-PHENYL-PYRIDAZINE(67820-83-1)
• EPA Substance Registry System: 6-CHLORO-4-METHYL-3-PHENYL-PYRIDAZINE(67820-83-1)

Safety Data

• Hazardous Substances Data: 67820-83-1(Hazardous Substances Data)

Usage

General Description

6-CHLORO-4-METHYL-3-PHENYL-PYRIDAZINE is a chemical compound with the molecular formula C11H9ClN2. It is a pyridazine derivative that contains a chloro and methyl group attached to the 6th and 4th carbon atoms, respectively, and a phenyl group attached to the 3rd carbon atom. 6-CHLORO-4-METHYL-3-PHENYL-PYRIDAZINE has potential applications in pharmaceutical and agrochemical industries due to its diverse biological activities and therapeutic properties. Studies have shown that 6-CHLORO-4-METHYL-3-PHENYL-PYRIDAZINE exhibits antimicrobial, antifungal, and anti-inflammatory properties, making it a promising candidate for the development of new drugs and pesticides. Furthermore, it is also used as an intermediate in organic synthesis for the production of various other chemical compounds.

InChI:InChI=1/C11H9ClN2/c1-8-7-10(12)13-14-11(8)9-5-3-2-4-6-9/h2-7H,1H3

Upstream product

• 19064-64-3 3,6-dichloro-4-methylpyridazine 
• 98-80-6 phenylboronic acid 
• 33048-55-4 5-Methyl-6-phenyl-3(2H)-pyridazinone 
• 93-55-0 1-phenyl-propan-1-one 
• 298-12-4 Glyoxilic acid 

Downstream Products

• 68206-21-3 4-methyl-3-phenylpyridazine 
• 105538-13-4 6-Amino-1-(3-ethoxycarbonyl-propyl)-4-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-65-3 6-Amino-1-(3-carboxy-propyl)-4-methyl-3-phenyl-pyridazin-1-ium; bromide 
• 105537-96-0 5-Methyl-6-phenyl-pyridazin-3-ylamine 
• 33048-55-4 5-Methyl-6-phenyl-3(2H)-pyridazinone 
• 140149-41-3 (5-Methyl-6-phenyl-pyridazin-3-yl)-hydrazine 

Relevant articles and documents

Pyridazine N-Oxides as Precursors of Metallocarbenes: Rhodium-Catalyzed Transannulation with Pyrroles

Pyridazine N-oxides are used for the first time as precursors of metallocarbenes. These nitrogen-rich heterocycles led to the discovery of a novel acceptor and donor-acceptor enalcarbenoids. The synthetic utility of these metallocarbenes was demonstrated in the rhodium-catalyzed denitrogenative transannulation of pyridazine N-oxides with pyrroles to the valuable alkyl, 7-aryl, and 7-styryl indoles. The transannulation strategy was applied to the synthesis of a potent anticancer agent.

Pyridazine derivatives

The present invention relates to pyridazine derivatives of formula: STR1 which are useful as ligands of cholinergic receptors, in particular, receptors of the M1 type.

USE OF 5-ALKYLPYRIDAZINE DERIVATIVES AS DRUGS ACTIVE ON THE CHOLINERGIC SYSTEM

The invention relates to the use of 5-alkylpyridazine derivatives of the formula STR1 in which R 1 is a C 1-C 4 alkyl group or a phenyl group and R 2 and R 3 independently are a C 1-C. sub. 4 alkyl group, or R 2 and R 3, taken with the nitrogen atom to wh