67845-46-9

Basic information

• Product Name: ACETALDEHYDE, PARA-METHYL PHENOXY
• Synonyms: (4-methylphenoxy)-acetaldehyd;(4-methylphenoxy)-Acetaldehyde;p-Cresoxyacetaldehyde;p-Methylphenyloxyacetaldehyde;XI ALDEHYDE;ACETALDEHYDE, PARA-METHYL PHENOXY;Acetaldehyde, (4-methylphenoxy)-;2-(4-Methylphenoxy)-acetaldehyde
• CAS NO: 67845-46-9
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.17
• EINECS: 267-317-6
• Mol File: 67845-46-9.mol

Chemical Properties

• Melting Point: 140-142 °C
• Boiling Point: 244.1°Cat760mmHg
• Flash Point: 104.2°C
• Appearance: /
• Density: 1.046g/cm³
• Vapor Pressure: 0.0309mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: ACETALDEHYDE, PARA-METHYL PHENOXY(CAS DataBase Reference)
• NIST Chemistry Reference: ACETALDEHYDE, PARA-METHYL PHENOXY(67845-46-9)
• EPA Substance Registry System: ACETALDEHYDE, PARA-METHYL PHENOXY(67845-46-9)

Safety Data

• Hazardous Substances Data: 67845-46-9(Hazardous Substances Data)

Usage

Uses

Used in Chemical Production Industry:
Acetaldehyde, para-methyl phenoxy is used as a key component in the synthesis of resins, dyes, and medicines, contributing to the development of a wide range of products across various industries.
Used as a Solvent:
In the manufacturing process, acetaldehyde, para-methyl phenoxy serves as a solvent for cellulose acetate and nitrocellulose, enabling the production of materials with specific properties and applications.
Used in Flavoring and Fragrance Industry:
This chemical compound is utilized as a flavoring agent and fragrance, adding distinctive scents and tastes to various consumer products, such as food, beverages, and cosmetics.

InChI:InChI=1/C9H10O2/c1-8-2-4-9(5-3-8)11-7-6-10/h2-6H,7H2,1H3

Upstream product

• 134254-23-2 mephenesin 
• 23431-48-3 allyl p-tolyl ether 
• 106-44-5 p-cresol 
• 940-64-7 2-(4-methylphenoxy)acetic acid 
• 15149-10-7 2-(4-methylphenoxy)ethanol 
• 5651-90-1 1-methyl-4-(2-propynyloxy)benzene 
• 2186-24-5 cresyl-glicidyl ether 
• 91142-23-3 1-(but-2-yn-1-yloxy)-4-methylbenzene 
• 66614-56-0 1-(2,2-diethoxyethoxy)-4-methylbenzene 

Downstream Products

• 22094-52-6 α-(p-Tolyloxy-ethyliden)-adipinsaeurediethylester 
• 1370283-13-8 C₁₈H₁₇N₃O₃S 
• 1370283-18-3 C₁₈H₁₇N₃O₂S₂ 
• 528567-69-3 C₂₂H₂₅NO₅ 
• 113080-10-7 Acetic acid (S)-1-cyano-2-p-tolyloxy-ethyl ester 
• 106985-60-8 4-methylphenoxyacetaldehyde cyanohydrin acetate 
• 66614-55-9 4-methylphenoxyacetaldehyde cyanohydrin 
• 134671-23-1 C₁₀H₁₄N₄O₂*H₂O₄S 
• 22094-56-0 α-(p-Tolyloxy-ethyliden)-sebacinsaeurediethylester 
• 22094-48-0 α-(p-Tolyloxy-ethyliden)-glutarsaeurediethylester 

Relevant articles and documents

Thiocyanate radical mediated dehydration of aldoximes with visible light and air

We developed a new means of activating aldoximes by an in situ generated thiocyanate radical from ammonium thiocyanate and molecular oxygen at room temperature. With a catalytic amount of organic dye aizenuranine as the photocatalyst, the dehydration of aldoximes proceeds smoothly under visible light irradiation, providing a simple to handle, excellent functional group tolerance, and metal-free protocol for a wide range of nitriles.

New class of bioluminogenic probe based on bioluminescent enzyme-induced electron transfer: BioLeT

Bioluminescence imaging (BLI) has advantages for investigating biological phenomena in deep tissues of living animals, but few design strategies are available for functional bioluminescent substrates. We propose a new design strategy (designated as bioluminescent enzyme-induced electron transfer: BioLeT) for luciferin-based bioluminescence probes. Luminescence measurements of a series of aminoluciferin derivatives confirmed that bioluminescence can be controlled by means of BioLeT. Based on this concept, we developed bioluminescence probes for nitric oxide that enabled quantitative and sensitive detection even in vivo. Our design strategy should be applicable to develop a wide range of practically useful bioluminogenic probes.

The synthesis of some new hydrazone derivatives containing the benzothiazole moiety

Hydrazones are an important class of compounds found in many synthetic products. Due to their importance in synthetic chemistry, the present article reports the synthesis of a new series of ten compounds based on the coupling of 2-oxo-3(2H)-benzothiazoleacetic acid, hydrazide and 2-thioxo-3(2H)- -benzothiazoleacetic acid, hydrazide with different aldehydes. The structures of the synthesized compounds were confirmed by elemental analyses, IR, 1H- -NMR, 13C-NMR and FAB+-MS spectral data. Copyright 2012 (CC) SCS.

Synthesis of aryloxyacetaldehydes and N-(aryloxyethyl)cyclohexanamine hydrochloroides

Oxidation of 2-(aryloxymethyl)oxiranes with periodic acid gave a series of aryloxyacetaldehydes which reacted with cyclohexylamine in THF, and subsequent reduction of Schiff bases thus obtained with sodium tetrahydridoborate resulted in the formation of the corresponding secondary amines which were isolated and characterized as hydrochlorides.

Wacker oxidation of terminal olefins in a mixture of [bmim][BF4] and water

A simple and efficient PdCl2/CuCl catalyzed oxidation of alkenes has been successfully developed using a mixture of water and the ionic liquid [bmim][BF4] as solvent. Starting from various types of terminal olefins, the corresponding ketones have been prepared under mild reaction conditions and obtained in good to excellent yields after a simple extraction with diethyl ether. Furthermore, it was possible to recycle and reuse the ionic liquid and the catalytic system.

Ozonolysis of Olefins VIII [1]. Synthesis of Phenoxyacetaldehydes by Ozonolysis of Allylphenylethers

A new route for the preparation of a series of phenoxyacetaldehydes (2a-j) which are useful intermediates or products, is described. It starts from the easily available allylphenylethers 1a-j which are ozonized at -40°C and further treated with dimethylsulfide to give solutions of the corresponding phenoxyacetaldehydes 2a-j; these are purified by column chromatography. Reaction of 2a-j with 1-methyl-1-phenylhydrazine leads to the corresponding hydrazones 3a-c, 3e-g, 3i, and 3j. The aldehydes can also be transformed into the stable dimethylcetals 4a, 4e, 4h, and 4i by reaction with trimethyl orthoformate.

Formation of Optically Active Aryloxyacetaldehyde Cyanohydrin Acetates with the Aid of a Microorganism

Microorganisms that hydrolyze the one enantiomer of dl-phenoxyacetaldehyde cyanohydrin acetate were screened, and Bacillus coagulans isolated from soil was found to be the best.This bacterium was applied to the asymmetric hydrolysis of other aryloxyacetaldehyde derivatives to give satisfactory results.The effect of adding dimethyl sulfoxide to the medium is also described.