67869-16-3

Basic information

• Product Name: dimethyl 3-benzoylphthalate
• Synonyms: dimethyl 3-benzoylphthalate
• CAS NO: 67869-16-3
• Molecular Weight: 298.295
• Mol File: 67869-16-3.mol

Chemical Properties

• CAS DataBase Reference: dimethyl 3-benzoylphthalate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 3-benzoylphthalate(67869-16-3)
• EPA Substance Registry System: dimethyl 3-benzoylphthalate(67869-16-3)

Safety Data

• Hazardous Substances Data: 67869-16-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 602-82-4 3-benzoylphthalic acid 
• 591-51-5 phenyllithium 
• 5779-93-1 2,3-dimethylbenzaldehyde 
• 21945-69-7 (2,3-dimethylphenyl)(phenyl)methanol 
• 6453-99-2 3-benzoylthiophene 
• 762-42-5 dimethyl acetylenedicarboxylate 

Relevant articles and documents

COMPOUND HAVING BET INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREFOR

The invention relates to the field of pharmaceutical chemistry. Specifically, the present invention relates to a series of BET (bromodomain and extra-terminal domain) inhibitors having a novel structure, particularly inhibitors targeting BRD4 (Bromodomain-containing protein 4), and a preparation method and use therefor. The structure thereof is shown in the following general formula (I). Said compounds or a stereoisomer, racemate, geometric isomer, tautomer, prodrug, hydrate, solvate, or crystal form thereof, or a pharmaceutically acceptable salt thereof, and the pharmaceutical compsosition thereof can be used for the treatment and/or prevention of related diseases mediated by bromodomain proteins.

Gold-Catalyzed Ring Expansion of Enyne-Lactone: Generation and Transformation of 2-Oxoninonium

An efficient gold-catalyzed ring-expansion reaction of enyne-lactones to form 2-oxoninonium intermediates is reported. The 2-oxoninonium generated in this work could undergo further 6π electrocyclization and aromatization reaction to produce different aromatic compounds.