67886-69-5

Usage

Uses

Used in Organic Synthesis:
Naphthalene, 2-iodo-6-methoxy(9CI) is used as a building block in organic synthesis for the preparation of various compounds. Its unique structure allows for the formation of new chemical bonds and the creation of diverse molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Naphthalene, 2-iodo-6-methoxy(9CI) is utilized as a key intermediate in the synthesis of biologically active molecules and pharmaceutical intermediates. Its presence in these molecules can contribute to their therapeutic properties and potential use in treating various diseases and conditions.
Used in Drug Development:
Naphthalene, 2-iodo-6-methoxy(9CI) has potential applications in the development of new drugs and therapeutic agents. Its unique chemical structure can be leveraged to design and create novel compounds with improved pharmacological properties, such as increased potency, selectivity, and reduced side effects.
Used as a Reference Standard:
In analytical testing and research, Naphthalene, 2-iodo-6-methoxy(9CI) may also be used as a reference standard. This allows for the accurate identification, quantification, and quality control of related compounds and substances in various applications, ensuring the reliability and validity of experimental results.

InChI:InChI=1/C11H9IO/c1-13-11-5-3-8-6-10(12)4-2-9(8)7-11/h2-7H,1H3

Upstream product

• 93-04-9 2-Methoxynaphthalene 
• 32721-21-4 1-iodo-2-methoxynapthalene 
• 5111-65-9 2-Bromo-6-methoxynaphthalene 
• 7732-18-5 water 
• 109-72-8 n-butyllithium 

Downstream Products

• 127053-22-9 4-(6'-methoxy-2'-naphthyl)-3-buten-2-one 
• 627536-34-9 [2-(2'-hydroxy-6'-trifluoromethyl-[1,1']binaphthalenyl-2-ylamino)-ethyl]-(2,4,6-trimethyl-phenyl)-carbamic acid tert-butyl ester 
• 1378521-72-2 C₁₉H₁₈O 
• 93-04-9 2-Methoxynaphthalene 
• 1278587-56-6 C₂₂H₁₉⁽²⁾HN₂O₂ 
• 1278587-54-4 1-methyl-2-(4-methoxyphenyl)-5-(6-methoxy-2-naphthyl)-1H-imidazole 
• 1278587-57-7 1-methyl-2-(4-methanesulfinyl-2-methylphenyl)-5-(6-methoxynaphthalen-2-yl)-1H-imidazole 
• 1278587-40-8 1-methyl-2-(2-methoxyphenyl)-5-(6-methoxy-2-naphthyl)-1H-imidazole 
• 1278587-39-5 1-methyl-2-(2-methylphenyl)-5-(6-methoxy-2-naphthyl)-1H-imidazole 

Relevant academic research and scientific papers

N6-arylation of 2′-deoxyadenosine via copper-catalyzed direct coupling with aryl halides

(Chemical Equation Presented) A general method for efficient N 6-arylation of 2′-deoxyadenosine via copper-catalyzed direct coupling with aryl iodides and bromides is described. The method is useful for aryl halides with either electron-donatin

Direct C-C bond construction from arylzinc reagents and aryl halides without external catalysts

Direct cross-coupling between an arylzinc reagent and an aryl halide was accomplished without any external catalyst, enabling efficient and selective formation of the corresponding biaryl compound with broad functional group compatibility. Direct cross-coupling between a diarylzinc compound and an aryl iodide was accomplished without using any external catalyst. The reaction is efficient and selective, enabling formation of the corresponding biaryl compounds with broad functional group compatibility. The reaction is proposed to proceed by a thermally initiated single electron transfer (SET) route. Copyright

REACTIVE MESOGENIC COMPOUNDS AND MIXTURES

The invention relates to new reactive mesogenic compounds (RM), polymerisable liquid crystal (LC) mixtures and polymers comprising them, and the use of the compounds, mixtures and polymers in optical, electrooptical, electronic, semiconducting or luminescent components or devices, in decorative, security or cosmetic applications, especially for use in polymer films having high optical dispersion.

Chiral Ru-based complexes for asymmetric olefin metathesis: Enhancement of catalyst activity through steric and electronic modifications

Design, synthesis, characterization, and catalytic activity of six enantiomerically pure Ru-based metathesis catalysts are disclosed (3a-3f). The new chiral catalysts were prepared through steric and electronic alterations of the parent catalyst system (3

Lipase-mediated asymmetric construction of 2-arylpropionic acids: Enantiocontrolled syntheses of S-naproxen and S-ibuprofen

A general and enantiocontrolled synthetic route to 2-arylpropionic acids, represented by non-steroidal anti-inflammatory drugs S-naproxen 1a and S-ibuprofen 1b, has been developed by employing the lipase-mediated asymmetric acetylation of prochiral 2-aryl-1,3-propanediol 3, which has been derived via a Heck reaction, as the key step.

Method of inhibiting leukotriene biosynthesis by oral administration of p-aminophenols or derivatives thereof

A method is provided for inhibiting leukotriene biosynthesis and thus treating asthma, psoriasis or inflammation by oral administration of p-aminophenols having the structure STR1 wherein m is 0 to 5; X is CH or N; R1 and R2 may be the same or different and are H, lower alkyl, aryl, hydroxy, hydroxyalkyleneoxy, alkylthio, alkoxy, alkanoyloxy, aryloxy, halo, carboxy, alkoxycarbonyl or amido; R3 is H, lower alkyl, alkanoyl or aroyl; and R4 is H, lower alkyl, benzoyl or alkanoyl, and including acid-addition salts thereof, with the proviso that when R4 is benzoyl, R2 is other than H.

Quinoline compounds and compositions thereof

p-Aminophenols are provided having the structure STR1 wherein m is 0 to 5; X is CH or N; R1 and R2 may be the same or different and are H, lower alkyl, aryl, hydroxy, hydroxyalkyleneoxy, alkylthio, alkoxy, alkanoyloxy, aryloxy, halo, carboxy, alkoxycarbonyl or amido; R3 is H, lower alkyl, alkanoyl or aroyl; and R4 is H, lower alkyl or alkanoyl, and including acid-addition salts thereof, with the proviso that when X is CH, m is 0 and R1 is H, and when R4 is H, R2 is other than alkoxy, H or hydroxy, and when R4 is benzoyl, R2 is other than H. These compounds together with the compounds defined in the above proviso are useful as inhibitors of leukotriene production and as such are useful as antiallergy, anti-inflammatory and anti-psoriatic agents.

HYDROFORMYLATION CATALYSED BY RHODIUM COMPLEXES OF TREHALOSE-DERIVED LIGANDS αα and ββ-TREDIP; A HIGHLY REGIOSELECTIVE ROUTE TO α-METHYLARYLPROPIONALDEHYDES

Rhodium complexes of the ligand αα-TREDIP give 62:1 iso-regioselectivity in the hydroformylation of styrene under ambient conditions without excess posphine, higher than any previously reported value.The results are compared with those obtained with other ligands, and extended to preparation of 2-(6-methoxy-2-naphthyl)-propanal, a precursor of the anti-inflammatory drug naproxen.