679-84-5

Usage

Uses

Used in Pesticide Industry:
Halopropane is used as a chemical reagent for the preparation of pesticides. Its reactivity and stability make it a valuable component in the synthesis of various pesticides that are effective in controlling pests and protecting crops.
Used in Pharmaceutical Industry:
Halopropane is used as a chemical intermediate in the development of novel tyrosinase inhibitors. Tyrosinase is an enzyme involved in the production of melanin, and its inhibition can have applications in the treatment of hyperpigmentation disorders and in the cosmetic industry for skin lightening products.

InChI:InChI=1/C3H3BrF4/c4-1-3(7,8)2(5)6/h2H,1H2

Upstream product

• 115-17-3 bromal 
• 88399-68-2 2-(2,2,3,3-tetrafluoropropoxy)-4,5-benzo-1,3,2-dioxaphospholane 
• 506-68-3 bromocyane 
• 65611-17-8 tris(2,2,3,3,4,4,5,5-octafluoropentyl) phosphite 
• 76-37-9 2,2,3,3-tetrafluoropropanol 
• 129416-46-2 2,2-bis(2-bromo-3,3,3-trichloroethoxy)-2-(2,2,3,3-tetrafluoropropoxy)-1,3,2λ⁵-benzodioxaphosphole 
• 129416-45-1 2,2-bis(2,3,3,3-tetrabromoethoxy)-2-(2,2,3,3-tetrafluoropropoxy)-1,3,2λ⁵-benzodioxaphosphole 
• 66959-14-6 2,2,3,3-tetrafluoropropyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate 
• 65675-12-9 1,1,3-trihydroperfluoropropyl benzenesulfonate 
• 2241-68-1 tris(2,2,3,3-tetrafluoropropyl)phosphite 
• 786-31-2 p-toluenesulfonic acid-2,2,3,3-tetrafluoropropyl ester 

Downstream Products

• 158664-13-2 2,3,3-trifluoroprop-1-ene 
• 205521-85-3 benzyl 2,2,3,3-tetrafluoropropyl sulfide 

Relevant academic research and scientific papers

HYDROFLUOROOLEFINS AND METHODS OF USING SAME

A hydrofluoroolefin compound represented by the following general formula (II): Formula (II) where Rf is a linear, branched, or cyclic perfluoroalkyl group having 1-6 carbon atoms, and optionally comprises at least one catenated heteroatom selected from nitrogen or oxygen; n is 0 or 1; X is Cl or Br; with the following proviso: when Rf is CF3, then n is 1.

Alternative synthetic routes to hydrofluoroolefins

A series of hydrofluoroolefins with -CF=CH2, -CH=CHF and -CH=CF2 groups were designed and prepared via various synthetic routes, including HX or BrF elimination, Wittig-type olefination or fluorination using SF4.

α,α,ω-TRIHYDRO-α-HALOPERFLUOROALKANES

A synthesis has been developed for α,α,ω-trihydrohaloperfluoroalkanes, H(CF2CF2)n*CH2X, where X is Cl or Br and n is 1 or 4.It is based on the cleavage of the aromatic sulfonate esters of α,α,ω-trihydroperfluoroalkan-α-ols by alkali metal halides.

INSERTION REACTIONS IN THE P-Hal BOND IN PHOSPHORANES. SYNTHESIS OF 1(1-HALOALKOXYL)PHOSPHORANES

Functionally substituted (1-haloalkoxy)phosphoranes were synthesized by the reactions of cyclic, bicyclic, and acyclic mono-, di-, and tri-halophosphoranes with chloral and bromal.

α,α-DISUBSTITUTED POLYFLUOROALKANES

The reaction of 1,1,ω-trihydropolyfluoro-1-alkanols with triphenyldichloro- and triphenyldibromophosphorus gave 1-chloro- and 1-bromo-1,1,ω-trihydropolyfluoroalkanes.The 1,2-elimination of HF from the alkanes by the action of basic agents led to the formation of 1-chloro(bromo)-1,ω-dihydropolyfluoro-1-alkenes in the E form. 1,2-Dehalogenation (1-Br, 2-F) of the 1-bromo-1,1,ω-trihydropolyfluoroalkanes by the action of zinc made it possible to obtain the 1,1,ω-trihydropolyfluoro-1-alkenes. 1,2-Dehalogenation (1-Cl, 2-F) of the 1-chloro-1,1,ω-trihydropolyfluoroalkanes does not take place under analogous conditions.

SYNTHESIS OF THREE PARTIALLY FLUORINATED ALKANESULFONIC ACIDS AS POTENTIAL FUEL-CELL ELECTROLYTES.

The simple and effective syntheses of CH//2FCH//2SO//3H, CF//3CH//2SO//3H, AND CHF//2CF//2CH//2SO//3H have been achieved with 18. 8%, 34. 1%, and 33. 7% overall yields. The low molecuar weight partially fluorinated alkanesulfonic acids containing alpha -methylene groups can be prepared from the p-toluenesulfonates of the corresponding alcohols, via a reaction with benzyl mercaptan, followed by an oxidative chlorination of the resulting sulfides, with subsequent hydrolysis of the sulfonyl chloride. The reaction of partially fluorinated alkyl halides with sodium sulfite (Strecker's method) proved to be inefficient (very low yields) and unreliable. The sulfonate salts formed are difficult to recover and purify.