67903-42-8Relevant academic research and scientific papers
A convenient one-pot synthesis of homoallylic halides and 1,3-butadienes
Wong, Ken-Tsung,Hung, Ying-Yueh
, p. 8033 - 8036 (2003)
An efficient one-pot synthetic pathway for the preparation of homoallylic halides by in situ generated MgBrCl-promoted ring opening of cyclopropylcarbinyl acetates has been established. An easily accessible one-pot synthetic protocol of 1,3-butadienes by the elimination of hydrogen halides from the resulting homoallylic halides in the presence of an excess amount of strong base has also been developed.
Highly Stereoselective Positional Isomerization of Styrenes via Acid-Catalyzed Carbocation Mechanism
Hu, Xiao-Si,He, Jun-Xiong,Zhang, Ying,Zhou, Jian,Yu, Jin-Sheng
supporting information, p. 2227 - 2233 (2021/06/28)
The first transition metal-free highly stereoselective positional isomerization of various α-alkyl styrenes through a carbocation mechanism triggered strategy is developed by using Al(OTf)3 as a hidden Br?nsted acid catalyst, which provides facile access to value-added acyclic tri- and tetra-substituted alkenes in good yields with high stereoselectivity under mild conditions. The practicality of this protocol is further highlighted by the gram-scale synthesis, high stereoselectivity, good functional group tolerance, and simple operation. Mechanistic studies support that Al(OTf)3 acts as a hidden Br?nsted acid catalyst and a carbocation intermediate is formed.
Amination of arenes through electron-deficient reaction cascades of aryl epoxyazides
Lang, Stuart,Kennedy, Alan R.,Murphy, John A.,Payne, Andrew H.
, p. 3655 - 3658 (2007/10/03)
(Matrix presented) Aryl epoxyazides undergo efficient electron-deficient reaction cascades mediated by Lewis acids, leading to regiospecific amination of the aromatic ring.
