67928-33-0

Basic information

• Product Name: (S)-N-(p-Methoxybenzylidene)-2-amino-1-butanol
• Synonyms: (S)-N-(p-Methoxybenzylidene)-2-amino-1-butanol
• CAS NO: 67928-33-0
• Molecular Weight: 207.272
• Mol File: 67928-33-0.mol

Chemical Properties

• CAS DataBase Reference: (S)-N-(p-Methoxybenzylidene)-2-amino-1-butanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-(p-Methoxybenzylidene)-2-amino-1-butanol(67928-33-0)
• EPA Substance Registry System: (S)-N-(p-Methoxybenzylidene)-2-amino-1-butanol(67928-33-0)

Safety Data

• Hazardous Substances Data: 67928-33-0(Hazardous Substances Data)

Upstream product

• 5856-62-2 (S)-2-aminobutan-1-ol 
• 26227-73-6 N-(4-methoxybenzylidene)-4-(n-butyl)aniline 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant articles and documents

Derivatives of (R) and (S)-2-amino-1-butanol as possible anti-arrhythmics

The chiral imines derived from (R) and (S)-2-amino-1-butanol have been reported.Some of the chiral imines have been found to be in equilibrium with the corresponding 1,3-oxazolidines, which on treatment with sodium borohydride in methanol are reduced to the corresponding N-benzyl derivatives.

Use of Liquid Crystal Induced Circular Dichroism for Absolute Configurational Assignments of β-Amino Alcohols

Dissolution of small quantities of chiral β-amino alcohols in liquid crystalline N-(p-methoxybenzylidene)-p-n-butylaniline (MBBA) results in induced rotations due to the formation of a cholesteric (chiral) liquid crystal phase.The induced rotations are several orders of magnitude larger than those observed for β-amino alcohols in isotropic solutions, and the signs of these rotations can be correlated with the absolute configurations of the chiral amino alcohols when standard conformational analysis arguments and the preference of elongated molecules to align with MBBA are considered.