679404-77-4

Upstream product

• 14199-63-4 1-deoxymannojirimycin 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 679404-78-5 2,6-di-O-pivaloyl-N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-D-mannitol 
• 760966-01-6 6-O-pivaloyl-N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-D-mannitol 
• 868632-13-7 6-O-(5'-azidopentyl)-1,5-dideoxy-1-[2-(N-phenylsulfonylindol-3-yl)ethyl]-1,5-imino-2,3-O-isopropylidene-4-O-methoxymethyl-D-mannitol 
• 868632-10-4 6-O-(5'-azidopentyl)-N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-2,3-O-isopropylidene-4-O-methoxymethyl-D-mannitol 
• 868632-06-8 N-benzyloxycarbonyl-6-O-tert-butyldimethylsilyl-1,5-dideoxy-1,5-imino-2,3-O-isopropylidene-4-O-methoxymethyl-D-mannitol 
• 868632-05-7 N-benzyloxycarbonyl-6-O-tert-butyldimethylsilyl-1,5-dideoxy-1,5-imino-2,3-O-isopropylidene-D-mannitol 
• 868632-08-0 N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-2,3-O-isopropylidene-4-O-methoxymethyl-D-mannitol 
• 868632-03-5 N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-2,3-O-isopropylidene-D-mannitol 

Relevant academic research and scientific papers

Synthesis of an iminosugar based peptidomimetic analogue

The synthesis of an 1-deoxymannojirimycin based analogue of a known HIV-protease inhibitor is described. The strategies employed for introduction of the pharmacophore groups onto the azasugar scaffold were based on regioselective reactions of the hydroxyl

Synthesis of peptidomimetics based on iminosugar and β-D- glucopyranoside scaffolds and inhibiton of HIV-protease

Synthetic routes to peptidomimetic compounds derived from saccharide scaffolds are described. The regioselective introduction of pivaloyl groups was achieved from N-benzyloxycarbonyl protected 1-deoxymannojirimycin or via D-fructopyranosides. The results from biological evaluation of the saccharide derivatives as HIV-protease inhibitors are included.