760966-01-6Relevant articles and documents
Synthesis of peptidomimetics based on iminosugar and β-D- glucopyranoside scaffolds and inhibiton of HIV-protease
Chery, Florence,Cronin, Linda,O'Brien, Julie L.,Murphy, Paul V.
, p. 6597 - 6608 (2004)
Synthetic routes to peptidomimetic compounds derived from saccharide scaffolds are described. The regioselective introduction of pivaloyl groups was achieved from N-benzyloxycarbonyl protected 1-deoxymannojirimycin or via D-fructopyranosides. The results from biological evaluation of the saccharide derivatives as HIV-protease inhibitors are included.