67976-98-1

Usage

InChI:InChI=1/C21H11NO/c1-2-6-13-12(5-1)9-10-18-16(13)11-17-14-7-3-4-8-15(14)20-21(23-20)19(17)22-18/h1-11H

Upstream product

• 224-42-0 dibenz[a,j]acridine 
• 105467-76-3 1,4,8,9-tetrahydrodibenzacridine 
• 105483-69-0 1,4,10,13-tetrahydrodibenzacridine 
• 105467-77-4 1,2,3,4-tetrahydrodibenzacridine 
• 2217-43-8 6-amino-1,2,3,4-tetrahydronaphthalene 
• 5419-02-3 1-dimethylaminomethyl-naphthalen-2-ol 

Downstream Products

• 67977-03-1 6-hydroxydibenzacridine 
• 105467-64-9 trans-5,6-dihydro-5,6-dihydroxydibenzacridine 

Relevant academic research and scientific papers

Mono-, and Dibenzacridine Imines. Synthesis of 1a,11b-Dihydrobenzazirinoacridine, 4b,5a-Dihydrodibenzazirinoacridine and 1a,13b-Dihydrodibenzazirinoacridine

The syntheses of the K-imine derivatives of benzacridine, dibenzacridine and dibenzacridine are described.The parent hydrocarbons 1, 6 and 11 were oxidized with sodium hypochlorite under phase transfer conditions to the corresponding K-oxides 4, 9 and 14, which in turn were reacted with sodium azide.The resulting azido alcohols were then cyclized with tributylphosphine to the title compounds 5, 10 and 15.

Synthesis of Potential Metabolites of Dibenzacridine: Dihydro Diols and Phenols

The potential trans dihydro diol metabolites of the carcinogen dibenzacridine (1) were prepared.The dihydro diols trans-1,2-dihydroxydibenzacridine (12) and trans-3,4-dihydro-3,4-dihydroxydibenzacridine (13) were prepared by Prevost reactio